[HTML][HTML] AC/EBPβ isoform recruits the SWI/SNF complex to activate myeloid genes
E Kowenz-Leutz, A Leutz - Molecular cell, 1999 - cell.com
The activation of many genes requires the concerted effort of two or more transcription factors.
Although C/EBPβ is known to cooperate with Myb to induce transcription of the granulocyte…
Although C/EBPβ is known to cooperate with Myb to induce transcription of the granulocyte…
Cooperation between C/EBPα TBP/TFIIB and SWI/SNF recruiting domains is required for adipocyte differentiation
TĊ Pedersen, E Kowenz-Leutz, A Leutz… - Genes & …, 2001 - genesdev.cshlp.org
Chromatin remodeling is an important step in promoter activation during cellular lineage
commitment and differentiation. We show that the ability of the C/EBPα transcription factor to …
commitment and differentiation. We show that the ability of the C/EBPα transcription factor to …
Novel mechanism of C/EBP beta (NF-M) transcriptional control: activation through derepression.
E Kowenz-Leutz, G Twamley, S Ansieau… - Genes & …, 1994 - genesdev.cshlp.org
Phosphorylation of transcription factors is regarded as a major mechanism to control their
activity in regulation of gene expression. C/EBP beta is a transcription factor that becomes …
activity in regulation of gene expression. C/EBP beta is a transcription factor that becomes …
Phosphorylation of CREB affects its binding to high and low affinity sites: implications for cAMP induced gene transcription.
…, F Weih, W Schmid, C DeVack, E Kowenz‐Leutz… - The EMBO …, 1992 - embopress.org
Cyclic AMP treatment of hepatoma cells leads to increased protein binding at the cyclic AMP
response element (CRE) of the tyrosine aminotransferase (TAT) gene in vivo, as revealed …
response element (CRE) of the tyrosine aminotransferase (TAT) gene in vivo, as revealed …
Myb and NF-M: combinatorial activators of myeloid genes in heterologous cell types.
SA Ness, E Kowenz-Leutz, T Casini… - Genes & …, 1993 - genesdev.cshlp.org
The c-Myb transcription factor regulates the differentiation of immature erythroid, lymphoid,
and myeloid cells, although only the latter cells become transformed by the v-myb oncogene. …
and myeloid cells, although only the latter cells become transformed by the v-myb oncogene. …
[PDF][PDF] Ras induces mediator complex exchange on C/EBPβ
X Mo, E Kowenz-Leutz, H Xu, A Leutz - Molecular cell, 2004 - cell.com
C/EBPβ is an intrinsically repressed transcription factor that regulates genes involved in
differentiation, proliferation, tumorigenesis, and apoptosis. C/EBPβ acts as a repressor that is …
differentiation, proliferation, tumorigenesis, and apoptosis. C/EBPβ acts as a repressor that is …
SIRT1 regulates macrophage self‐renewal
…, CJ Busch, J Favret, E Kowenz‐Leutz… - The EMBO …, 2017 - embopress.org
Mature differentiated macrophages can self‐maintain by local proliferation in tissues and
can be extensively expanded in culture under specific conditions, but the mechanisms of this …
can be extensively expanded in culture under specific conditions, but the mechanisms of this …
[HTML][HTML] G9a-mediated lysine methylation alters the function of CCAAT/enhancer-binding protein-β
O Pless, E Kowenz-Leutz, M Knoblich, J Lausen… - Journal of biological …, 2008 - ASBMB
The functional capacity of the transcriptional regulatory CCAAT/enhancer-binding protein-β (C/EBPβ)
is governed by protein interactions and post-translational protein modifications. In …
is governed by protein interactions and post-translational protein modifications. In …
Crosstalk between C/EBPβ phosphorylation, arginine methylation, and SWI/SNF/Mediator implies an indexing transcription factor code
E Kowenz‐Leutz, O Pless, G Dittmar, M Knoblich… - The EMBO …, 2010 - embopress.org
Cellular signalling cascades regulate the activity of transcription factors that convert
extracellular information into gene regulation. C/EBPβ is a ras/MAPkinase signal‐sensitive …
extracellular information into gene regulation. C/EBPβ is a ras/MAPkinase signal‐sensitive …
The NF‐M transcription factor is related to C/EBP beta and plays a role in signal transduction, differentiation and leukemogenesis of avian myelomonocytic cells.
S Katz, E Kowenz‐Leutz, C Müller, K Meese… - The EMBO …, 1993 - embopress.org
Retroviral oncogenes encode nuclear regulators of gene expression or signal transduction
molecules, such as protein kinases, which stimulate the activity of cellular transcription factors…
molecules, such as protein kinases, which stimulate the activity of cellular transcription factors…