[HTML][HTML] Identification of novel malaria transmission-blocking vaccine candidates
E Takashima, M Tachibana, M Morita… - Frontiers in Cellular …, 2021 - frontiersin.org
Control measures have significantly reduced malaria morbidity and mortality in the last two
decades; however, the downward trends have stalled and have become complicated by the …
decades; however, the downward trends have stalled and have become complicated by the …
Immune evasion of Plasmodium falciparum by RIFIN via inhibitory receptors
…, NMQ Palacpac, S Itagaki, S Iwanaga, E Takashima… - Nature, 2017 - nature.com
Malaria is among the most serious infectious diseases affecting humans, accounting for
approximately half a million deaths each year 1 . Plasmodium falciparum causes most life-…
approximately half a million deaths each year 1 . Plasmodium falciparum causes most life-…
Application of wheat germ cell-free protein expression system for novel malaria vaccine candidate discovery
TU Arumugam, D Ito, E Takashima… - Expert review of …, 2014 - Taylor & Francis
Malaria causes about 216 million clinical cases and 0.7 million deaths annually. One
promising route to address malaria is vaccination. However, so far, not even a single licensed …
promising route to address malaria is vaccination. However, so far, not even a single licensed …
Functional comparison of Plasmodium falciparum transmission-blocking vaccine candidates by the standard membrane-feeding assay
K Miura, E Takashima, B Deng, G Tullo… - Infection and …, 2013 - Am Soc Microbiol
Recently, there has been a renewed interest in the development of transmission-blocking
vaccines (TBV) against Plasmodium falciparum malaria. While several candidate TBVs have …
vaccines (TBV) against Plasmodium falciparum malaria. While several candidate TBVs have …
[HTML][HTML] Plasmodium vivax transmission-blocking vaccines: Progress, challenges and innovation
M Tachibana, E Takashima, M Morita… - Parasitology …, 2022 - Elsevier
Existing control measures have significantly reduced malaria morbidity and mortality in the
last two decades, although these reductions are now stalling. Significant efforts have been …
last two decades, although these reductions are now stalling. Significant efforts have been …
Development and validation of serological markers for detecting recent Plasmodium vivax infection
RJ Longley, MT White, E Takashima, J Brewster… - Nature medicine, 2020 - nature.com
A major gap in the Plasmodium vivax elimination toolkit is the identification of individuals
carrying clinically silent and undetectable liver-stage parasites, called hypnozoites. This study …
carrying clinically silent and undetectable liver-stage parasites, called hypnozoites. This study …
[HTML][HTML] Targets of complement-fixing antibodies in protective immunity against malaria in children
…, PM Siba, FJI Fowkes, E Takashima… - Nature …, 2019 - nature.com
Antibodies against P. falciparum merozoites fix complement to inhibit blood-stage replication
in naturally-acquired and vaccine-induced immunity; however, specific targets of these …
in naturally-acquired and vaccine-induced immunity; however, specific targets of these …
Host immunity to Plasmodium falciparum and the assessment of emerging artemisinin resistance in a multinational cohort
…, K O'Flaherty, E Takashima… - Proceedings of the …, 2017 - National Acad Sciences
Artemisinin-resistant falciparum malaria, defined by a slow-clearance phenotype and the
presence of kelch13 mutants, has emerged in the Greater Mekong Subregion. Naturally …
presence of kelch13 mutants, has emerged in the Greater Mekong Subregion. Naturally …
Identification of highly-protective combinations of Plasmodium vivax recombinant proteins for vaccine development
…, J Healer, C Chitnis, AF Cowman, E Takashima… - Elife, 2017 - elifesciences.org
10.7554/eLife.28673.001 The study of antigenic targets of naturally-acquired immunity is
essential to identify and prioritize antigens for further functional characterization. We measured …
essential to identify and prioritize antigens for further functional characterization. We measured …
Contribution of Sialic Acid-Binding Adhesin to Pathogenesis of Experimental Endocarditis Caused by Streptococcus gordonii DL1
Y Takahashi, E Takashima, K Shimazu… - Infection and …, 2006 - Am Soc Microbiol
An insertional mutation in hsa, the gene encoding the sialic acid-binding adhesin of
Streptococcus gordonii DL1, resulted in a significant reduction of the infection rate of the organism …
Streptococcus gordonii DL1, resulted in a significant reduction of the infection rate of the organism …