[HTML][HTML] Structural basis of SARS-CoV-2 and SARS-CoV antibody interactions

E Gavor, YK Choong, SY Er, H Sivaraman… - Trends in …, 2020 - cell.com
The 2019 coronavirus pandemic remains a major public health concern. Neutralizing
antibodies (nAbs) represent a cutting-edge antiviral strategy. We focus here on severe acute …

Structural basis of SARS-CoV-2–and SARS-CoV–receptor binding and small-molecule blockers as potential therapeutics

…, SY Er, YK Choong, E Gavor… - Annual Review of …, 2021 - annualreviews.org
Over the past two decades, deadly coronaviruses, with the most recent being the severe acute
respiratory syndrome-related coronavirus-2 (SARS-CoV-2) 2019 pandemic, have majorly …

Structure of Aedes aegypti carboxypeptidase B1‐inhibitor complex uncover the disparity between mosquito and non‐mosquito insect carboxypeptidase inhibition …

E Gavor, YK Choong, C Jobichen, YK Mok… - Protein …, 2021 - Wiley Online Library
Metallocarboxypeptidases (MCPs) in the mosquito midgut play crucial roles in infection, as
well as in mosquito dietary digestion, reproduction, and development. MCPs are also part of …

[HTML][HTML] Identification of Aedes aegypti salivary gland proteins interacting with human immune receptor proteins

E Gavor, YK Choong, Y Liu, J Pompon… - PLoS Neglected …, 2022 - journals.plos.org
Mosquito saliva proteins modulate the human immune and hemostatic systems and control
mosquito-borne pathogenic infections. One mechanism through which mosquito proteins …

Structural and functional characterization of Aedes aegypti pupal cuticle protein that controls dengue virus infection

Q Huang, E Gavor, NK Tulsian, J Fan, Q Lin… - Protein …, 2023 - Wiley Online Library
The pupal cuticle protein from Aedes aegypti (AaPC) inhibits dengue virus (DENV) infection;
however, the underlying mechanism of this inhibition remains unknown. Here, we report …

Structure of Aedes aegypti procarboxypeptidase B1 and its binding with Dengue virus for controlling infection

E Gavor, YK Choong, NK Tulsian… - Life Science …, 2022 - life-science-alliance.org
Metallocarboxypeptidases play critical roles in the development of mosquitoes and influence
pathogen/parasite infection of the mosquito midgut. Here, we report the crystal structure of …

[HTML][HTML] Recognition of Aedes aegypti Mosquito Saliva Protein LTRIN by the Human Receptor LTβR for Controlling the Immune Response

SN Loh, IR Anthony, E Gavor, XS Lim, RM Kini, YK Mok… - Biology, 2024 - mdpi.com
Simple Summary In this study, we present the characterization of Aedes aegypti mosquito
salivary protein, LTRIN (lymphotoxin β receptor inhibitor), a key facilitator of ZIKV transmission. …

Down-regulation of Id1 and Id3 genes affects growth and survival of Human Umbilical Vein Endothelial Cells (HUVECs)

…, DB Asante, JAM Edekor, E Sarpong, E Gavor… - Journal of Applied …, 2016 - jabonline.in
Inhibitors of DNA (Id) proteins have been implicated in cell growth, cell cycle control, apoptosis
and angiogenesis. Studies reveal that Id1 and Id3 may be required for angiogenesis in …

Investment behaviour of rural families in Ghana: The case of rural families in the Ho municipality of the Volta region

…, C Offei-Ansah, ME Gavor - International Journal of …, 2012 - search.proquest.com
The main objective of the study was to explore the investment behaviour of rural households
in the Ho Municipality of Ghana. The population used for the study was rural families in the …

Differences in the dynamics of the tandem-SH2 modules of the Syk and ZAP-70 tyrosine kinases.

HT Hobbs, NH Shah, JM Badroos, CL Gee… - PROTEIN … - ncbi.nlm.nih.gov
The Syk-family tyrosine kinases, Syk and ZAP-70, play paralogous roles in the adaptive
immune system, operating in B cells and T cells respectively. Despite their similar roles and …