User profiles for E. L. Sibille
 | Etienne SibilleCAMH & University of Toronto (Psychiatry & Pharmacology) Verified email at camh.ca Cited by 12910 |
Impaired hippocampal-dependent learning and functional abnormalities in the hippocampus in mice lacking serotonin1A receptors
Z Sarnyai, EL Sibille, C Pavlides… - Proceedings of the …, 2000 - National Acad Sciences
The hippocampus is a major limbic target of the brainstem serotonergic neurons that
modulate fear, anxiety, and learning through postsynaptic serotonin 1A receptors (5-HT 1A …
modulate fear, anxiety, and learning through postsynaptic serotonin 1A receptors (5-HT 1A …
Genetic and pharmacological disruption of neurokinin 1 receptor function decreases anxiety-related behaviors and increases serotonergic function
…, G Gobbi, PC Debs, EL Sibille… - Proceedings of the …, 2001 - National Acad Sciences
Alterations in serotonin (5-hydroxytriptamine, 5-HT), norepinephrine, and γ-aminobutyric acid
have been linked to the pathophysiology of anxiety and depression, and medications that …
have been linked to the pathophysiology of anxiety and depression, and medications that …
Brain-derived neurotrophic factor levels in late-life depression and comorbid mild cognitive impairment: a longitudinal study
Abstract Changes in brain-derived neurotrophic factor (BDNF) level are implicated in the
pathophysiology of cognitive decline in depression and neurodegenerative disorders in older …
pathophysiology of cognitive decline in depression and neurodegenerative disorders in older …
Genetic risk for schizophrenia and psychosis in Alzheimer disease
…, J Williams, R Mayeux, OL Lopez, EL Sibille… - Molecular …, 2018 - nature.com
Psychotic symptoms, defined as the occurrence of delusions or hallucinations, are frequent
in Alzheimer disease (AD), affecting~ 40 to 60% of individuals with AD (AD with psychosis (…
in Alzheimer disease (AD), affecting~ 40 to 60% of individuals with AD (AD with psychosis (…
[HTML][HTML] Abnormal left-sided orbitomedial prefrontal cortical–amygdala connectivity during happy and fear face processing: a potential neural mechanism of female …
JRC Almeida, DM Kronhaus, EL Sibille… - Frontiers in …, 2011 - frontiersin.org
Background: Pathophysiologic processes supporting abnormal emotion regulation in major
depressive disorder (MDD) are poorly understood. We previously found abnormal inverse left…
depressive disorder (MDD) are poorly understood. We previously found abnormal inverse left…
Positive Allosteric Modulation of α5-GABAA Receptors Reverses Stress-Induced Alterations in Dopamine System Function and Prepulse Inhibition of Startle
Background Up to 64% of patients diagnosed with posttraumatic stress disorder (PTSD)
experience psychosis, likely attributable to aberrant dopamine neuron activity. We have …
experience psychosis, likely attributable to aberrant dopamine neuron activity. We have …
Expression of dopamine D2 and D3 receptors in the human retina revealed by positron emission tomography and targeted mass spectrometry
Dopamine D 2 receptors (D 2 R) are expressed in the human retina and play an important role
in the modulation of neural responses to light-adaptation. However, it is unknown whether …
in the modulation of neural responses to light-adaptation. However, it is unknown whether …
Extrasynaptic localization is essential for α5GABAA receptor modulation of dopamine system function
Dopamine system dysfunction, observed in animal models with psychosis-like symptomatology,
can be restored by targeting Gamma-Aminobutyric Acid type A receptors (GABA A R) …
can be restored by targeting Gamma-Aminobutyric Acid type A receptors (GABA A R) …
[HTML][HTML] VSNL1 co-expression networks in aging include calcium signaling, synaptic plasticity, and Alzheimer's disease pathways
… Sibille have no conflicts of interest or financial interests to declare. The Review Editor
Konasale Prasad declares that, despite being affiliated to the same institution as authors Chien-…
Konasale Prasad declares that, despite being affiliated to the same institution as authors Chien-…
Rate of brain aging and APOE ε4 are synergistic risk factors for Alzheimer's disease
…, SS Lee, DA Bennett, EL Sibille… - Life science …, 2019 - life-science-alliance.org
Advanced age and the APOE ε4 allele are the two biggest risk factors for Alzheimer’s
disease (AD) and declining cognitive function. We describe a universal gauge to measure …
disease (AD) and declining cognitive function. We describe a universal gauge to measure …