Myrf is a key transcription factor for oligodendrocyte differentiation and central nervous system
myelination. We and others have previously shown that Myrf is generated as a membrane …

Oligodendrocytes (OLs) produce myelin in the central nervous system (CNS), which
accelerates the propagation of action potentials and supports axonal integrity. As a major …

PRC2 creates the repressive mark histone H3 Lys27 trimethylation. Although PRC2 is involved
in various biological processes, its role in glial development remains ambiguous. Here, …

Murine neural stem cells (NSCs) were recently shown to release piRNA-containing
exosomes/microvesicles (Ex/Mv) for exerting antiviral immunity, but it remains unknown if these Ex/…

Purpose Mercury (Hg) is a nonessential and toxic metal that is widely distributed in the
environment. This study was performed to estimate the representative blood Hg level, to …

Mapping enhancers to genes is a fundamental goal of modern biology. We have developed
an innovative strategy that maps enhancers to genes in a principled manner. We illustrate its …

Olig2 is a basic helix–loop–helix transcription factor that plays a critical role in the central
nervous system. It directs the specification of motor neurons and oligodendrocyte precursor …

Oligodendrocytes (OLs) produce myelin sheaths around axons in the central nervous system
(CNS). Myelin accelerates the propagation of action potentials along axons and supports …

Myrf is a membrane-bound transcription factor that plays a key role in various biological
processes. The Intramolecular Chaperone Auto-processing (ICA) domain of Myrf forms a homo-…

Myrf is a pleiotropic membrane-bound transcription factor that plays critical roles in diverse
organisms, including in oligodendrocyte differentiation, embryonic development, molting, and …