User profiles for Dong-Woo Hwang

Dong Woo Hwang

Research Fellow, Albert Einstein College of Medicine
Verified email at einsteinmed.edu
Cited by 101

A DNA repair pathway can regulate transcriptional noise to promote cell fate transitions

RV Desai, X Chen, B Martin, S Chaturvedi, DW Hwang… - Science, 2021 - science.org
INTRODUCTION Fluctuations have long been known to dynamically shape microstate
distributions in physical systems. Throughout engineering, “dithering” approaches that modulate …

Real-time single-molecule imaging of transcriptional regulatory networks in living cells

DW Hwang, A Maekiniemi, RH Singer… - Nature Reviews …, 2024 - nature.com
Gene regulatory networks drive the specific transcriptional programmes responsible for the
diversification of cell types during the development of multicellular organisms. Although our …

[HTML][HTML] Spatiotemporal insights into RNA–organelle interactions in neurons

SC Kharod, DW Hwang, S Das… - Frontiers in Cell and …, 2021 - frontiersin.org
Neurons exhibit spatial compartmentalization of gene expression where localization of
messenger RNAs (mRNAs) to distal processes allows for site-specific distribution of proteins …

Dopamine D2 receptors in hilar mossy cells regulate excitatory transmission and hippocampal function

…, JJ Lebowitz, C Ramos, DW Hwang… - Proceedings of the …, 2023 - National Acad Sciences
Hilar mossy cells (MCs) are principal excitatory neurons of the dentate gyrus (DG) that play
critical roles in hippocampal function and have been implicated in brain disorders such as …

Chromatin-mediated translational control is essential for neural cell fate specification

DW Hwang, A Jaganathan, P Shrestha… - Life Science …, 2018 - life-science-alliance.org
Neural cell fate specification is a multistep process in which stem cells undergo sequential
changes in states, giving rise to particular lineages such as neurons and astrocytes. This …

Ethanol-induced developmental neurodegeneration in secretin receptor-deficient mice

DW Hwang, B Givens, I Nishijima - Neuroreport, 2009 - journals.lww.com
Alcohol exposure during brain development induces neuronal cell death in the brain. Several
neuroactive peptides have been shown to protect against alcohol-induced cell death. …

[HTML][HTML] Dopamine D2 receptors in mossy cells reduce excitatory transmission and are essential for hippocampal function

MC Gulfo, JJ Lebowitz, C Ramos, DW Hwang… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Hilar mossy cells (MCs) are principal excitatory neurons of the dentate gyrus (DG) that play
critical roles in hippocampal function and have been implicated in brain disorders such as …

Phosphorylation alters FMRP granules and determines their transport or protein synthesis abilities

SC Kharod, D Hwang, H Choi, KJ Yoon, PE Castillo… - bioRxiv, 2023 - biorxiv.org
Fragile X messenger ribonucleoprotein (FMRP) is an RNA-binding protein that can form
granules within neurons. Although FMRP-containing Fragile X granules have been extensively …

Durability study of blower motor noise

MH Lee, KD Ih, DW Hwang, HH Lee - Proceedings of the Korean …, 2007 - koreascience.kr
As in many of the vehicle NVH issues, blower motor noise has been improved over the years
through intensive R&D and production process improvement. Durability of motors, however…

The tumor suppressor CHD5 is an epigenetic regulator of neuronal cell fate

AA Mills, DW Hwang - Cancer Research, 2014 - AACR
Genomic lesions affecting the 1p36 chromosomal region are prevalent in variety of human
malignancies, yet the tumor suppressor in this region had not been identified. We used …