User profiles for Debashis Sahoo
Debashis SahooAssociate Professor of Pediatrics and Computer Science, University of California San Diego Verified email at ucsd.edu Cited by 11813 |
The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors
…, JP Volkmer, AJ Gentles, D Sahoo… - Proceedings of the …, 2012 - National Acad Sciences
CD47, a “don't eat me” signal for phagocytic cells, is expressed on the surface of all human
solid tumor cells. Analysis of patient tumor and matched adjacent normal (nontumor) tissue …
solid tumor cells. Analysis of patient tumor and matched adjacent normal (nontumor) tissue …
Single-cell dissection of transcriptional heterogeneity in human colon tumors
Cancer is often viewed as a caricature of normal developmental processes, but the extent to
which its cellular heterogeneity truly recapitulates multilineage differentiation processes of …
which its cellular heterogeneity truly recapitulates multilineage differentiation processes of …
[PDF][PDF] Identification of the human skeletal stem cell
Stem cell regulation and hierarchical organization of human skeletal progenitors remain
largely unexplored. Here, we report the isolation of a self-renewing and multipotent human …
largely unexplored. Here, we report the isolation of a self-renewing and multipotent human …
Fusobacterium nucleatum promotes colorectal cancer by inducing Wnt/β‐catenin modulator Annexin A1
Fusobacterium nucleatum, a Gram‐negative oral anaerobe, is a significant contributor to
colorectal cancer. Using an in vitro cancer progression model, we discover that F. nucleatum …
colorectal cancer. Using an in vitro cancer progression model, we discover that F. nucleatum …
Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age
WW Pang, EA Price, D Sahoo… - Proceedings of the …, 2011 - National Acad Sciences
In the human hematopoietic system, aging is associated with decreased bone marrow
cellularity, decreased adaptive immune system function, and increased incidence of anemia and …
cellularity, decreased adaptive immune system function, and increased incidence of anemia and …
[HTML][HTML] Combined analysis of murine and human microarrays and ChIP analysis reveals genes associated with the ability of MYC to maintain tumorigenesis
The MYC oncogene has been implicated in the regulation of up to thousands of genes
involved in many cellular programs including proliferation, growth, differentiation, self-renewal, …
involved in many cellular programs including proliferation, growth, differentiation, self-renewal, …
[HTML][HTML] Identification and specification of the mouse skeletal stem cell
How are skeletal tissues derived from skeletal stem cells? Here, we map bone, cartilage,
and stromal development from a population of highly pure, postnatal skeletal stem cells (mouse …
and stromal development from a population of highly pure, postnatal skeletal stem cells (mouse …
[HTML][HTML] CDX2 as a prognostic biomarker in stage II and stage III colon cancer
Background The identification of high-risk stage II colon cancers is key to the selection of
patients who require adjuvant treatment after surgery. Microarray-based multigene-expression …
patients who require adjuvant treatment after surgery. Microarray-based multigene-expression …
Aged skeletal stem cells generate an inflammatory degenerative niche
Loss of skeletal integrity during ageing and disease is associated with an imbalance in the
opposing actions of osteoblasts and osteoclasts 1 . Here we show that intrinsic ageing of …
opposing actions of osteoblasts and osteoclasts 1 . Here we show that intrinsic ageing of …
An antibody against SSEA-5 glycan on human pluripotent stem cells enables removal of teratoma-forming cells
An important risk in the clinical application of human pluripotent stem cells (hPSCs), including
human embryonic and induced pluripotent stem cells (hESCs and hiPSCs), is teratoma …
human embryonic and induced pluripotent stem cells (hESCs and hiPSCs), is teratoma …