User profiles for David J Barry
 | David J BarryFrancis Crick Institute Verified email at crick.ac.uk Cited by 1263 |
Isoform diversity in the Arp2/3 complex determines actin filament dynamics
The Arp2/3 complex consists of seven evolutionarily conserved subunits (Arp2, Arp3 and
ARPC1–5) and plays an essential role in generating branched actin filament networks during …
ARPC1–5) and plays an essential role in generating branched actin filament networks during …
Open source software for quantification of cell migration, protrusions, and fluorescence intensities
Cell migration is frequently accompanied by changes in cell morphology (morphodynamics)
on a range of spatial and temporal scales. Despite recent advances in imaging techniques, …
on a range of spatial and temporal scales. Despite recent advances in imaging techniques, …
CD9 identifies pancreatic cancer stem cells and modulates glutamine metabolism to fuel tumour growth
Pancreatic ductal adenocarcinoma (PDAC) shows great cellular heterogeneity, with pronounced
epithelial and mesenchymal cancer cell populations. However, the cellular hierarchy …
epithelial and mesenchymal cancer cell populations. However, the cellular hierarchy …
[PDF][PDF] Ena/VASP proteins cooperate with the WAVE complex to regulate the actin cytoskeleton
Ena/VASP proteins and the WAVE regulatory complex (WRC) regulate cell motility by virtue
of their ability to independently promote actin polymerization. We demonstrate that Ena/…
of their ability to independently promote actin polymerization. We demonstrate that Ena/…
APC/C dysfunction limits excessive cancer chromosomal instability
Intercellular heterogeneity, exacerbated by chromosomal instability (CIN), fosters tumor
heterogeneity and drug resistance. However, extreme CIN correlates with improved cancer …
heterogeneity and drug resistance. However, extreme CIN correlates with improved cancer …
Condensin-mediated remodeling of the mitotic chromatin landscape in fission yeast
The eukaryotic genome consists of DNA molecules far longer than the cells that contain them.
They reach their greatest compaction during chromosome condensation in mitosis. This …
They reach their greatest compaction during chromosome condensation in mitosis. This …
A FIJI macro for quantifying pattern in extracellular matrix
Diverse extracellular matrix patterns are observed in both normal and pathological tissue.
However, most current tools for quantitative analysis focus on a single aspect of matrix …
However, most current tools for quantitative analysis focus on a single aspect of matrix …
Using machine learning methods in airline flight data monitoring to generate new operational safety knowledge from existing data
J Oehling, DJ Barry - Safety science, 2019 - Elsevier
The aim of this work is to investigate the possibility of using machine learning (ML) methods
in order to generate novel, safety-relevant knowledge from existing flight data. Airlines …
in order to generate novel, safety-relevant knowledge from existing flight data. Airlines …
MICAL2 enhances branched actin network disassembly by oxidizing Arp3B-containing Arp2/3 complexes
The mechanisms regulating the disassembly of branched actin networks formed by the Arp2/3
complex still remain to be fully elucidated. In addition, the impact of Arp3 isoforms on the …
complex still remain to be fully elucidated. In addition, the impact of Arp3 isoforms on the …
Estimating runway veer-off risk using a Bayesian network with flight data
DJ Barry - Transportation Research Part C: Emerging …, 2021 - Elsevier
Risk assessments in airline operations are mostly qualitative, despite abundant data from
programmes such as flight data monitoring (FDM) and flight operations quality assurance (…
programmes such as flight data monitoring (FDM) and flight operations quality assurance (…