Gene-expression analysis studies from Schultz et al. estimate that more than 2,300 genes in
the mouse genome are expressed predominantly in the male germ line. As of their 2003 …

Extracellular matrix (ECM), which provides critical scaffolds for all adhesive cells, regulates
proliferation, differentiation, and apoptosis. Different cell types employ customized ECMs, …

The mammalian spermatozoa produced in the testis require functional maturation in the
epididymis for their full competence. Epididymal sperm maturation is regulated by lumicrine …

An emerging family of extracellular matrix proteins characterized by 12 consecutive CSPG
repeats and the presence of Calx-β motif(s) includes Fras1, QBRICK/Frem1, and Frem2. …

The physiological roles of proteolysis are not limited to degrading unnecessary proteins.
Proteolysis plays pivotal roles in various biological processes through cleaving peptide bonds …

Using forward genetics, we have identified the genes mutated in two classes of zebrafish fin
mutants. The mutants of the first class are characterized by defects in embryonic fin …

More than 1000 genes are predicted to be predominantly expressed in mouse testis, yet
many of them remain unstudied in terms of their roles in spermatogenesis and sperm function …

In terrestrial vertebrates, spermatozoa generated in the testis are transported through the
reproductive tract toward outside the body. In addition to as the pathway of sperm transport, the …

The premature fusion of the paired frontal bones results in metopic craniosynostosis (MC)
and gives rise to the clinical phenotype of trigonocephaly. Deletions of chromosome 9p22.3 …

Background: Polydom/SVEP1 is a putative extracellular matrix protein of unknown function.
Results: Polydom/SVEP1 is a potent ligand for integrin α9β1 and colocalizes with the integrin …