User profiles for D. C. Jans
Daniel C. JansUniversity Medical Center of Göttingen & Max Planck Institute for biophysical Chemistry Verified email at mpibpc.mpg.de Cited by 1922 |
Bax assembles into large ring‐like structures remodeling the mitochondrial outer membrane in apoptosis
…, CA Wurm, C Brüser, D Neumann, DC Jans… - The EMBO …, 2016 - embopress.org
The Bcl‐2 family proteins Bax and Bak are essential for the execution of many apoptotic
programs. During apoptosis, Bax translocates to the mitochondria and mediates the …
programs. During apoptosis, Bax translocates to the mitochondria and mediates the …
[PDF][PDF] Rcf1 mediates cytochrome oxidase assembly and respirasome formation, revealing heterogeneity of the enzyme complex
…, HE Meyer, A Zieseniss, DM Katschinski, DC Jans… - Cell metabolism, 2012 - cell.com
… in the presence or absence of membrane potential (Dc) for indicated times. Samples were
… the presence or absence of membrane potential (Dc), treated with Proteinase K, solubilized …
… the presence or absence of membrane potential (Dc), treated with Proteinase K, solubilized …
MINOS1 is a conserved component of mitofilin complexes and required for mitochondrial function and cristae organization
AK Alkhaja, DC Jans, M Nikolov… - Molecular biology of …, 2012 - Am Soc Cell Biol
The inner membrane of mitochondria is especially protein rich and displays a unique
morphology characterized by large invaginations, the mitochondrial cristae, and the inner …
morphology characterized by large invaginations, the mitochondrial cristae, and the inner …
STED super-resolution microscopy reveals an array of MINOS clusters along human mitochondria
DC Jans, CA Wurm, D Riedel… - Proceedings of the …, 2013 - National Acad Sciences
The mitochondrial inner membrane organizing system (MINOS) is a conserved large hetero-oligomeric
protein complex in the mitochondrial inner membrane, crucial for the …
protein complex in the mitochondrial inner membrane, crucial for the …
[HTML][HTML] Dna-paint minflux nanoscopy
LM Ostersehlt, DC Jans, A Wittek, J Keller-Findeisen… - Nature …, 2022 - nature.com
MINimal fluorescence photon FLUXes (MINFLUX) nanoscopy, providing photon-efficient
fluorophore localizations, has brought about three-dimensional resolution at nanometer scales. …
fluorophore localizations, has brought about three-dimensional resolution at nanometer scales. …
[HTML][HTML] Breast cancer quantitative proteome and proteogenomic landscape
In the preceding decades, molecular characterization has revolutionized breast cancer (BC)
research and therapeutic approaches. Presented herein, an unbiased analysis of breast …
research and therapeutic approaches. Presented herein, an unbiased analysis of breast …
[PDF][PDF] Mic10 oligomerizes to bend mitochondrial inner membranes at cristae junctions
M Barbot, DC Jans, C Schulz, N Denkert, B Kroppen… - Cell metabolism, 2015 - cell.com
The mitochondrial inner membrane is highly folded and displays a complex molecular
architecture. Cristae junctions are highly curved tubular openings that separate cristae membrane …
architecture. Cristae junctions are highly curved tubular openings that separate cristae membrane …
The MICOS component Mic60 displays a conserved membrane-bending activity that is necessary for normal cristae morphology
D Tarasenko, M Barbot, DC Jans, B Kroppen… - Journal of Cell …, 2017 - rupress.org
The inner membrane (IM) of mitochondria displays an intricate, highly folded architecture
and can be divided into two domains: the inner boundary membrane adjacent to the outer …
and can be divided into two domains: the inner boundary membrane adjacent to the outer …
TIM29 is a subunit of the human carrier translocase required for protein transport
S Callegari, F Richter, K Chojnacka, DC Jans… - Febs …, 2016 - Wiley Online Library
Hydrophobic inner mitochondrial membrane proteins with internal targeting signals, such as
the metabolite carriers, use the carrier translocase (TIM22 complex) for transport into the …
the metabolite carriers, use the carrier translocase (TIM22 complex) for transport into the …
Neuronal Aβ42 is enriched in small vesicles at the presynaptic side of synapses
Y Yu, DC Jans, B Winblad, LO Tjernberg… - Life Science …, 2018 - life-science-alliance.org
… DC Jans acknowledges financial support for infrastructure development from the Swedish
Foundation for Strategic Research (RIF14-0091). B Winblad acknowledges financial support …
Foundation for Strategic Research (RIF14-0091). B Winblad acknowledges financial support …