The water-soluble, self-assembled, tetrahedral assembly K 12 Ga 4 L 6 (L = 1,5-biscatecholamidenaphthalene)
catalyzes the Nazarov cyclization of 1,3-pentadienols with extremely …

Widespread resistance to first-line TB drugs is a major problem that will likely only be resolved
through the development of new drugs with novel mechanisms of action. We have used …

The tetrahedral assembly [Ga 4 L 6 ] 12− [L = N,N-bis(2,3-dihydroxybenzoyl)-1,5-diaminonaphthalene)
encapsulates a variety of cations, including propargyl enammonium cations …

Multiple drug discovery initiatives for tuberculosis are currently ongoing to identify and
develop new potent drugs with novel targets in order to shorten treatment duration. One of the …

Respiration is a promising target for the development of new antimycobacterial agents, with
a growing number of compounds in clinical development entering this target space. However…

The kinetically controlled, regioselective deprotonation of cyclopentenyl cations is mediated
by encapsulation within a metal–ligand assembly. The regiochemistry of the deprotonation …

The self‐assembled supramolecular host [Ga 4 L 6 ] 12− (1; L=N,N‐bis(2,3‐dihydroxybenzoyl)‐1,5‐diaminonaphthalene)
catalyzes the Nazarov cyclization of 1,3‐pentadienols with …

The use of micellar conditions to enable one-pot reactions involving both transition metal and
enzymatic catalysts is reported. Representative enzymatic transformations under micellar …

The imidazo[2,1-b]thiazole-5-carboxamides (ITAs) are a promising class of anti-tuberculosis
agents shown to have potent activity in vitro and to target QcrB, a key component of the …

New antitubercular agents are needed to combat the spread of multidrug- and extensively
drug-resistant strains of Mycobacterium tuberculosis. The frontline antitubercular drug …