TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells
…, M Eickmann, O Dolnik, C Rohde… - Life science …, 2020 - life-science-alliance.org
The novel emerged SARS-CoV-2 has rapidly spread around the world causing acute
infection of the respiratory tract (COVID-19) that can result in severe disease and lethality. For …
infection of the respiratory tract (COVID-19) that can result in severe disease and lethality. For …
[PDF][PDF] Longitudinal isolation of potent near-germline SARS-CoV-2-neutralizing antibodies from COVID-19 patients
…, T Weber, MS Ercanoglu, L Gieselmann, C Rohde… - Cell, 2020 - cell.com
The SARS-CoV-2 pandemic has unprecedented implications for public health, social life,
and the world economy. Because approved drugs and vaccines are limited or not available, …
and the world economy. Because approved drugs and vaccines are limited or not available, …
[HTML][HTML] Safety and immunogenicity of a candidate Middle East respiratory syndrome coronavirus viral-vectored vaccine: a dose-escalation, open-label, non …
…, C Mair, R Makinson, J Sheridan, C Rohde… - The Lancet Infectious …, 2020 - thelancet.com
Background Cases of Middle East respiratory syndrome coronavirus (MERS-CoV) infection
continue to rise in the Arabian Peninsula 7 years after it was first described in Saudi Arabia. …
continue to rise in the Arabian Peninsula 7 years after it was first described in Saudi Arabia. …
Safety and immunogenicity of a modified vaccinia virus Ankara vector vaccine candidate for Middle East respiratory syndrome: an open-label, phase 1 trial
…, V Krähling, NMA Okba, S Halwe, C Rohde… - The Lancet Infectious …, 2020 - thelancet.com
Background The Middle East respiratory syndrome coronavirus (MERS-CoV) causes a
respiratory disease with a case fatality rate of up to 35%. Given its potential to cause a public …
respiratory disease with a case fatality rate of up to 35%. Given its potential to cause a public …
Immunogenicity and efficacy of the COVID-19 candidate vector vaccine MVA-SARS-2-S in preclinical vaccination
A Tscherne, JH Schwarz, C Rohde… - Proceedings of the …, 2021 - National Acad Sciences
Severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2) has emerged as
the infectious agent causing the pandemic coronavirus disease 2019 (COVID-19) with …
the infectious agent causing the pandemic coronavirus disease 2019 (COVID-19) with …
[HTML][HTML] Stabilized recombinant SARS-CoV-2 spike antigen enhances vaccine immunogenicity and protective capacity
…, DL Shin, A Fathi, C Rohde… - The Journal of …, 2022 - Am Soc Clin Investig
The SARS-CoV-2 spike (S) glycoprotein is synthesized as a large precursor protein and must
be activated by proteolytic cleavage into S1 and S2. A recombinant modified vaccinia virus …
be activated by proteolytic cleavage into S1 and S2. A recombinant modified vaccinia virus …
[HTML][HTML] Intranasal administration of a monoclonal neutralizing antibody protects mice against SARS-CoV-2 infection
…, K Vanshylla, F Liberta, H Gruell, M Zehner, C Rohde… - Viruses, 2021 - mdpi.com
Despite the recent availability of vaccines against severe acute respiratory syndrome
coronavirus type 2 (SARS-CoV-2), there is an urgent need for specific anti-SARS-CoV-2 drugs. …
coronavirus type 2 (SARS-CoV-2), there is an urgent need for specific anti-SARS-CoV-2 drugs. …
[HTML][HTML] Development and characterization of an indirect ELISA to detect SARS-CoV-2 spike protein-specific antibodies
V Krähling, S Halwe, C Rohde, D Becker… - Journal of …, 2021 - Elsevier
The current Severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) pandemic
is a public health emergency of international concern. Sensitive and precise diagnostic …
is a public health emergency of international concern. Sensitive and precise diagnostic …
[HTML][HTML] Short-and long-interval prime-boost vaccination with the candidate vaccines MVA-SARS-2-ST and MVA-SARS-2-S induces comparable humoral and cell …
…, A Freudenstein, JH Schwarz, L Limpinsel, C Rohde… - Viruses, 2023 - mdpi.com
The COVID-19 pandemic caused significant human health and economic consequences.
Due to the ability of SARS-CoV-2 to spread rapidly and to cause severe disease and mortality …
Due to the ability of SARS-CoV-2 to spread rapidly and to cause severe disease and mortality …
Development of an antibody capture ELISA using inactivated Ebola Zaire Makona virus
V Krähling, D Becker, C Rohde, M Eickmann… - Medical microbiology …, 2016 - Springer
The 2014 Zaire Ebola virus (ZEBOV) outbreak in West Africa represents an international
public health concern. Highly sensitive and precise diagnostic tools are needed. In the present …
public health concern. Highly sensitive and precise diagnostic tools are needed. In the present …