… Co.’s (Claudia Contadini) work has also been supported by AIRC IG2016-n.19069, and C.Ci.’s
(Claudia Cirotti) work has also been supported by a FIRC-AIRC fellowship for Italy “…

Caspase-8 was originally identified as a central player of programmed cell death triggered
by death receptor stimulation. In that context, its activity is tightly regulated through several …

Simple Summary Caspase-8 is a protease mediating the activation of the extrinsic apoptotic
process that leads to programmed cellular death. Evasion of apoptosis is one of the key …

Caspase-8 is a cysteine protease that plays an essential role in apoptosis. Consistently with
its canonical proapoptotic function, cancer cells may genetically or epigenetically …

Centrosomal p53 has been described for three decades but its role is still unclear. We
previously reported that, in proliferating human cells, p53 transiently moves to centrosomes at …

Glioblastoma is a severe brain tumor characterized by an extremely poor survival rate of
patients. Glioblastoma cancer cells escape to standard therapeutic protocols consisting of a …

Src is a non-receptor tyrosine kinase (TK) whose involvement in cancer, including glioblastoma
(GBM), has been extensively demonstrated. In this context, we started from our in-house …

Simple Summary Doxorubicin (DOX) is widely used in the treatment of breast cancer.
However, resistance limits its effectiveness. In particular, breast cancer stem cells (BCSCs) are …

Epidermal Growth Factor receptor (EGFR) is a tyrosine kinase receptor widely expressed on
the surface of numerous cell types, which activates several downstream signalling …

Listening in noisy environments requires effort- the active engagement of attention and
other cognitive abilities- as well as increased arousal. The ability to separately quantify the …