Duchenne muscular dystrophy (DMD) is a chronic muscle disease characterized by poor
myogenesis and replacement of muscle by extracellular matrix. Despite the shared genetic …

The amount and distribution of dystrophin protein in myofibers and muscle is highly variable
in Becker muscular dystrophy and in exon-skipping trials for Duchenne muscular dystrophy. …

Cardiomyopathy is a leading cause of death for Duchenne muscular dystrophy. Here, we
find that the mineralocorticoid receptor (MR) and glucocorticoid receptor (GR) can share …

Background We sought to identify microRNAs (miRNAs) associated with response to anti-TNF-α
or glucocorticoids in children with inflammatory bowel disease (IBD) to generate …

Objective Muscle inflammation is a feature in myositis and Duchenne muscular dystrophy (
DMD ). Autoimmune mechanisms are thought to contribute to muscle weakness in patients …

MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate important intracellular
biological processes. In myasthenia gravis (MG), a disease-specific pattern of elevated …

Background Becker muscular dystrophy (BMD) is a genetic neuromuscular disease of growing
importance caused by in‐frame, partial loss‐of‐function mutations in the dystrophin (DMD…

Corticosteroids are highly prescribed and effective anti-inflammatory drugs but the burden
of side effects with chronic use significantly detracts from patient quality of life, particularly in …

The development of therapeutics for muscle diseases such as facioscapulohumeral dystrophy
(FSHD) is impeded by a lack of objective, minimally invasive biomarkers. Here we identify …

Recently, the Food and Drug Administration granted accelerated approvals for four exon
skipping therapies–Eteplirsen, Golodirsen, Viltolarsen, and Casimersen–for Duchenne …