Mycobacteriophages are viruses that infect mycobacterial hosts such as Mycobacterium
smegmatis and Mycobacterium tuberculosis. All mycobacteriophages characterized to date are …

The genus Anaplasma consists of tick-transmitted obligate intracellular bacteria that invade
white or red blood cells to cause debilitating and potentially fatal infections. A. …

Intracellular bacteria that live in host cell–derived vacuoles are significant causes of human
disease. Parasitism of low-density lipoprotein (LDL) cholesterol is essential for many vacuole…

Anaplasma phagocytophilum is an emerging human pathogen and obligate intracellular
bacterium. It inhabits a host cell‐derived vacuole and cycles between replicative reticulate cell (…

Human granulocytic anaplasmosis (HGA) is a debilitating, non-specific febrile illness
caused by the granulocytotropic obligate intracellular bacterium called Anaplasma …

Background Allergy and allergic asthma are significant health burdens in developed countries
and are increasing in prevalence. Dendritic cells ( DC s) initiate immune responses to …

Ceramide-1-phosphate (C1P), a bioactive sphingolipid that regulates diverse processes
vital to mammalian physiology, is linked to disease states such as cancer, inflammation, and …

Anaplasma phagocytophilum is an obligate intracellular bacterial pathogen of humans and
animals. The A. phagocytophium-occupied vacuole (ApV) is a critical host-pathogen interface…

Anaplasma phagocytophilum infects neutrophils to cause granulocytic anaplasmosis. It
poorly infects mice deficient in acid sphingomyelinase (ASM), a lysosomal enzyme critical for …

Major depressive disorder (MDD) is a leading cause of disability worldwide and is marked by
symptoms such as decreased mood, hopelessness, feelings of guilt, and changes in sleep. …