Humoral and cellular responses to mRNA vaccines against SARS-CoV-2 in patients with a history of CD20 B-cell-depleting therapy (RituxiVac): an investigator …

…, VU Bacher, LY Mani, JM Iype, C Hirzel… - The Lancet …, 2021 - thelancet.com
Background B-cell-depleting therapies increase the risk of morbidity and mortality due to
COVID-19. Evidence-based SARS-CoV-2 vaccination strategies for patients on B-cell-depleting …

Nocardia Infection in Solid Organ Transplant Recipients: A Multicenter European Case-control Study

…, C Hirzel… - Reviews of Infectious …, 2016 - academic.oup.com
Background. Nocardiosis is a rare, life-threatening opportunistic infection, affecting 0.04% to
3.5% of patients after solid organ transplant (SOT). The aim of this study was to identify risk …

Burden and timeline of infectious diseases in the first year after solid organ transplantation in the Swiss Transplant Cohort Study

…, O Manuel, P Meylan, A Cusini, C Hirzel… - Clinical infectious …, 2020 - academic.oup.com
Background The burden and timeline of posttransplant infections are not comprehensively
documented in the current era of immunosuppression and prophylaxis. Methods In this …

[HTML][HTML] Toxoplasmosis in transplant recipients, Europe, 2010–2014

…, AH Groll, E Guy, C Hirzel… - Emerging infectious …, 2018 - ncbi.nlm.nih.gov
Transplantation activity is increasing, leading to a growing number of patients at risk for
toxoplasmosis. We reviewed toxoplasmosis prevention practices, prevalence, and outcomes for …

Vaccine-preventable infections among solid organ transplant recipients in Switzerland

…, C van Delden, M Mäusezahl, C Hirzel… - JAMA Network …, 2023 - jamanetwork.com
Importance Vaccine responses are decreased in solid organ transplant (SOT) recipients,
and given the complexity of implementation, vaccination programs may be suboptimal. The …

Outcome and treatment of nocardiosis after solid organ transplantation: new insights from a European study

…, M Fernández-Ruiz, J Dantal, C Hirzel… - Clinical infectious …, 2017 - academic.oup.com
In our study of 117 organ transplant recipients with nocardiosis, a history of tumor, invasive
fungal infection, donor age, and no acute rejection were independently associated with 1-…

Humoral and cellular immune responses on SARS-CoV-2 vaccines in patients with anti-CD20 therapies: a systematic review and meta-analysis of 1342 patients

…, A Limacher, A Born, MP Horn, B Maurer, C Hirzel… - RMD open, 2022 - rmdopen.bmj.com
Background Immune responses on SARS-CoV-2 vaccination in patients receiving anti-CD20
therapies are impaired but vary considerably. We conducted a systematic review and meta-…

Preventive strategies against cytomegalovirus and incidence of α‐herpesvirus infections in solid organ transplant recipients: a nationwide cohort study

…, N Khanna, K Boggian, C Hirzel… - American journal of …, 2017 - Wiley Online Library
We assessed the impact of antiviral preventive strategies on the incidence of herpes
simplex virus ( HSV ) and varicella‐zoster virus ( VZV ) infections in a nationwide cohort of …

[HTML][HTML] BK polyomavirus-specific 9mer CD8 T cell responses correlate with clearance of BK viremia in kidney transplant recipients: first report from the Swiss …

…, I Binet, D Golshayan, K Hadaya, C Hirzel… - American journal of …, 2017 - Elsevier
BK polyomavirus (BKPyV) causes premature kidney transplant (KT) failure in 1–15% of patients.
Because antivirals are lacking, most programs screen for BKPyV-viremia and, if positive, …

[HTML][HTML] Reduced monocytic human leukocyte antigen-DR expression indicates immunosuppression in critically ill COVID-19 patients

T Spinetti, C Hirzel, M Fux, LN Walti… - Anesthesia & …, 2020 - journals.lww.com
BACKGROUND: The cellular immune system is of pivotal importance with regard to the
response to severe infections. Monocytes/macrophages are considered key immune cells in …