Macrolides and ketolides comprise a family of clinically important antibiotics that inhibit
protein synthesis by binding within the exit tunnel of the bacterial ribosome. While these …

The foliar pathogen Pseudomonas syringae pv. syringae exhibits an exceptional ability to
survive on asymptomatic plants as an epiphyte. Intermittent wetting events on plants lead to …

Polyamines are essential metabolites that play an important role in cell growth, stress
adaptation and microbial virulence 1 , 2 – 3 . To survive and multiply within a human host, …

We report on the presence of a functional hydroxyectoine biosynthesis gene cluster,
ectABCD-ask, in Pseudomonas stutzeri DSM5190 T and evaluate the suitability of P. stutzeri …

In order to colonize a niche and compete for scarce resources, microorganisms have evolved
means to adjust the expression levels of their biosynthetic enzymes in response to the …

Although it is known that the amino acid sequence of a nascent polypeptide can impact its
rate of translation, dedicated tools to systematically investigate this process are lacking. Here, …

RESULTS Inverse toeprinting maps stalled ribosomes with codon resolution while preserving
the upstream coding region Ribosome profiling only generates a short footprint and thus …

While it has become increasingly apparent that the amino acid sequence of a nascent
polypeptide can modulate its rate of synthesis, tools to decipher the molecular basis underlying …

In all living cells ribosomes are responsible for the translation of genetic information into the
corresponding protein sequence. This central position does not only make them a valuable …

In the version of the Letter originally published, the ‘RR’motifs were incorrectly positioned
underneath 70S ribosomes in Fig. 1d; they should have been aligned to the beginning of …