Uveal melanoma, the most common eye malignancy, causes severe visual morbidity and is
fatal in approximately 50% of patients. Primary uveal melanoma can be cured by surgery or …

A high percentage of uveal melanoma patients develop metastatic tumors predominantly in
the liver. We studied the molecular profiles derived from gene expression microarrays and …

A significant proportion of patients with oestrogen receptor (ER) positive breast cancers (BC)
develop resistance to endocrine treatments (ET) and relapse with metastatic disease. Here …

Purpose Investigate in what extent sperm transcriptome of infertile men is different from that
of fertile individuals. Methods Semen samples were collected for determination of sperm …

Background & Aims Patients with hepatocellular carcinoma (HCC) displaying overexpression
of immune gene signatures are likely to be more sensitive to immunotherapy, however, the …

Muscle-invasive bladder cancer (BLCA) is an aggressive disease. Consensus BLCA
transcriptomic subtypes have been proposed, with two major Luminal and Basal subgroups, …

Purpose: Combined hepatocellular-cholangiocarcinoma (cHCC-CCA) is a rare malignancy
associated with an overall poor prognosis. We aimed to investigate the immune profile of …

Purpose: The consensus molecular subtypes (CMS) represent a significant advance in the
understanding of intertumor heterogeneity in colon cancer. Intratumor heterogeneity (ITH) is …

To ensure their high proliferation rate, tumor cells have an iron metabolic disorder causing
them to have increased iron needs, making them more susceptible to iron deprivation. This …

During epithelial‐mesenchymal transition (EMT), epithelial cells are converted into isolated
motile and invasive mesenchymal cells. In model systems, EMT is induced most often by the …