User profiles for Arne Mueller

Arne Müller

Research Associate, University of Leicester
Verified email at leicester.ac.uk
Cited by 142

Technical validation of real-world monitoring of gait: a multicentric observational study

…, W Maetzler, ME Micó-Amigo, A Mueller… - BMJ open, 2021 - bmjopen.bmj.com
Introduction Existing mobility endpoints based on functional performance, physical assessments
and patient self-reporting are often affected by lack of sensitivity, limiting their utility in …

[HTML][HTML] A roadmap to inform development, validation and approval of digital mobility outcomes: the Mobilise-D approach

L Rochester, C Mazzà, A Mueller, B Caulfield… - Digital …, 2020 - karger.com
Health care has had to adapt rapidly to COVID-19, and this in turn has highlighted a pressing
need for tools to facilitate remote visits and monitoring. Digital health technology, including …

[HTML][HTML] A multi-sensor wearable system for the assessment of diseased gait in real-world conditions

…, W Maetzler, EM Micó-Amigo, A Mueller… - … in Bioengineering and …, 2023 - frontiersin.org
Introduction: Accurately assessing people’s gait, especially in real-world conditions and in
case of impaired mobility, is still a challenge due to intrinsic and extrinsic factors resulting in …

[HTML][HTML] Assessing real-world gait with digital technology? Validation, insights and recommendations from the Mobilise-D consortium

…, S Koch, W Maetzler, D Megaritis, A Mueller… - … of neuroengineering and …, 2023 - Springer
Background Although digital mobility outcomes (DMOs) can be readily calculated from real-world
data collected with wearable devices and ad-hoc algorithms, technical validation is still …

Optimization of 3-pyrimidin-4-yl-oxazolidin-2-ones as allosteric and mutant specific inhibitors of IDH1

…, R Kulathila, F Lin, G Liu, A Mueller… - ACS Medicinal …, 2017 - ACS Publications
High throughput screening and subsequent hit validation identified 4-isopropyl-3-(2-((1-phenylethyl)amino)pyrimidin-4-yl)oxazolidin-2-one
as a potent inhibitor of IDH1 R132H . …

[HTML][HTML] Continuous digital monitoring of walking speed in frail elderly patients: noninterventional validation study and longitudinal clinical trial

A Mueller, HA Hoefling, A Muaremi… - JMIR mHealth and …, 2019 - mhealth.jmir.org
Background: Digital technologies and advanced analytics have drastically improved our
ability to capture and interpret health-relevant data from patients. However, only limited data …

Identification of Dlk1-Dio3 Imprinted Gene Cluster Noncoding RNAs as Novel Candidate Biomarkers for Liver Tumor Promotion

…, P Couttet, F Bolognani, A Mueller… - Toxicological …, 2013 - academic.oup.com
The molecular events during nongenotoxic carcinogenesis and their temporal order are
poorly understood but thought to include long-lasting perturbations of gene expression. Here, …

[HTML][HTML] Validity of accelerometry in step detection and gait speed measurement in orthogeriatric patients

AM Keppler, T Nuritidinow, A Mueller, H Hoefling… - PloS one, 2019 - journals.plos.org
Background Mobile accelerometry is a powerful and promising option to capture long-term
changes in gait in both clinical and real-world scenarios. Increasingly, gait parameters have …

[HTML][HTML] Mobilise-D insights to estimate real-world walking speed in multiple conditions with a wearable device

…, F Kluge, S Koch, W Maetzler, D Megaritis, A Mueller… - Scientific Reports, 2024 - nature.com
This study aimed to validate a wearable device’s walking speed estimation pipeline,
considering complexity, speed, and walking bout duration. The goal was to provide …

[HTML][HTML] Reverse engineering of digital measures: inviting patients to the conversation

…, CM Kanzler, L Leyens, K Lyden, A Mueller… - Digital …, 2023 - karger.com
Background: Digital measures offer an unparalleled opportunity to create a more holistic
picture of how people who are patients behave in their real-world environments, thereby …