Eukaryotic superfamily (SF) 1 helicases have been implicated in various aspects of RNA
metabolism, including transcription, processing, translation, and degradation. Nevertheless, …

Background & Aims Spinocerebellar ataxia type 3 ( SCA 3), also known as Machado‐Joseph
disease ( MJD ), is an autosomal dominantly inherited neurodegenerative disorder and the …

Many transcripts are targeted by nonsense-mediated decay (NMD), leading to their
degradation and the inhibition of their translation. We found that the protein SUZ domain–containing …

The CCR4-NOT complex is a multi-subunit complex in eukaryotes involved in many aspects
of mRNA regulation including transcription, translation and mRNA deadenylation. The …

All living systems rely on appropriate protein synthesis and therefore evolved intricate
mechanisms to control their proteome. Especially, the complexity of metazoan multicellular …

… I am also very grateful to Aoife hanet for her technical assistance and manuscript … Wang,
ZJ, Hanet, A., Weishäupl, D., Martins, IM, Sowa, AS, Riess, O. and Schmidt, T. (2018): Divalproex …

We noted recently that the injection of cells with a needle through a cystoscope in the urethral
sphincter muscle of pigs failed to deposit them nearby or at the intended target position in …

… Tikhon’s Orthodox University, Moscow Alexander Kurunczi, University Bochum Stefania
Maffeis, FU Berlin Aoife McInerney, University of Limerick Waltraud Meints-Stender, Lower …

The eukaryotic initiation factor 4E (eIF4E) binds the cap structure of an mRNA as the first
step of cap dependent translation. Together with the RNA helicase eIF4A and the scaffolding …

The multi-subunit CCR4-NOT complex is an important regulator of gene expression in
eukaryotes. It affects most steps of the messenger RNA (mRNA) lifecycle, but as the major …