With the completion of genome sequences of major model organisms, increasingly sophisticated
genetic tools are necessary for investigating the complex and coordinated functions of …

Background: Stigma toward mentally ill individuals acts as a barrier to accessing care and
receiving treatment. Aim: To review current evidence pertaining to stigma toward mental …

Pulmonary inflammation, which is characterized by the presence of perivascular macrophages,
has been proposed as a key pathogenic driver of pulmonary hypertension (PH), a …

In this report, we describe several approaches to improve the scalability and throughput of
major genetic crosses in ends-out gene targeting. We generated new sets of targeting vectors …

Latent infection with neurotropic herpes viruses, such as herpes simplex virus, type 1 (HSV1),
has been generally considered benign in most immunocompetent individuals except for …

The dynamic regulation of endothelial pathophenotypes in pulmonary hypertension (PH)
remains undefined. Cellular senescence is linked to PH with intracardiac shunts; however, its …

Myeloid cells, such as neutrophils, are produced in the bone marrow in high quantities and
are important in the pathogenesis of vascular diseases such as pulmonary hypertension (PH)…

Human cytomegalovirus (HCMV) infection is one of the leading prenatal causes of congenital
mental retardation and deformities world-wide. Access to cultured human neuronal …

Cancer therapies are being considered for treating rare noncancerous diseases like pulmonary
hypertension (PH), but effective computational screening is lacking. Via transcriptomic …

BACKGROUND: Consanguinity has been suggested as a risk factor for psychoses in some
Middle Eastern countries, but adequate control data are unavailable. Our recent studies in …