Background Human papillomavirus vaccines prevent human papillomavirus infection and
cervical precancers. The impact of vaccinating women with a current infection or after …

Cervical cancer is the second most common cancer in women worldwide, and knowledge
regarding its cause and pathogenesis is expanding rapidly. Persistent infection with one of …

During hypoxia, hypoxia-inducible factor-1α (HIF-1α) is required for induction of a variety of
genes including erythropoietin and vascular endothelial growth factor. Hypoxia increases …

Dendritic cells (DCs) express several receptors for the Fc portion of immunoglobulin (Ig)G (FcγR),
which mediate internalization of antigen–IgG complexes (immune complexes, ICs) and …

ContextViruslike particle human papillomavirus (HPV) vaccines were designed to prevent
HPV infection and development of cervical precancers and cancer. Women with oncogenic …

Persistent infections with carcinogenic human papillomaviruses (HPV) cause virtually all
cervical cancers. Cervical HPV types (n > 40) also represent the most common sexually …

Health professionals and the public need to understand the natural history of human
papillomavirus (HPV) infections of the cervix to best use the information provided by new molecular …

Intracellular bacteria and parasites typically invade host cells through the formation of an
internalization vacuole around the invading pathogen. Plasmodium sporozoites, the infective …

In order for cytotoxic T cells to initiate immune responses, peptides derived from internalized
antigens must be presented to the cytotoxic T cells on major histocompatibility complex (…

Background Human papillomavirus (HPV) infection, particularly with type 16, causes a growing
fraction of oropharyngeal cancers, whose incidence is increasing, mainly in developed …