Homologous recombination ( HR ) is a conserved mechanism that repairs broken chromosomes
via intact homologous sequences. How different genomic, chromatin and subnuclear …

The consequence of a mutation can be influenced by the context in which it operates. For
example, loss of gene function may be tolerated in one genetic background, and lethal in …

Heterochromatin is a conserved feature of eukaryotic chromosomes, with central roles in
gene expression regulation and maintenance of genome stability. How heterochromatin …

Eukaryotic cells have evolved a replication stress response that helps to overcome stalled/collapsed
replication forks and ensure proper DNA replication. The replication checkpoint …

Background Genetic suppression occurs when the deleterious effects of a primary “query”
mutation, such as a disease-causing mutation, are rescued by a suppressor mutation …

Eukaryotic chromosomes are replicated in interphase and the two newly duplicated sister
chromatids are held together by the cohesin complex and several cohesin auxiliary factors. …

Heterochromatin is a conserved feature of eukaryotic chromosomes, with central roles in
gene expression regulation and maintenance of genome stability. How DNA repair occurs in …

The consequence of a mutation can be influenced by the context in which it operates. For
example, loss of gene function may be tolerated in one genetic background, but lead to …

… Amandine BATTÉ …

… Amandine Batté’s present address is Center for Integrative Genomics, Université de Lausanne,
Lausanne-Dorigny, Switzerland. *Amandine Batté … replication fork progression Batté et al. …