[HTML][HTML] High-throughput screening yields several small-molecule inhibitors of repeat-associated non-AUG translation

…, UJ Sheth, BN Flores, SE Wright, AB Sutter… - Journal of Biological …, 2019 - ASBMB
Repeat-associated non-AUG (RAN) translation is a noncanonical translation initiation event
that occurs at nucleotide-repeat expansion mutations that are associated with several …

[HTML][HTML] Urinary tract infections trigger synucleinopathy via the innate immune response

…, A Kasen, M Aguileta, C Linstow, AB Sutter… - Acta …, 2023 - Springer
Symptoms in the urogenital organs are common in multiple system atrophy (MSA), also in
the years preceding the MSA diagnosis. It is unknown how MSA is triggered and these …

[HTML][HTML] Rational affinity maturation of anti-amyloid antibodies with high conformational and sequence specificity

…, CG Starr, JM Zupancic, SJ Moore, AB Sutter… - Journal of Biological …, 2021 - ASBMB
The aggregation of amyloidogenic polypeptides is strongly linked to several neurodegenerative
disorders, including Alzheimer's and Parkinson's diseases. Conformational antibodies …

Lysosomes Targeting pH Activable Imaging‐Guided Photodynamic Agents

…, H Anton, C Sutter, C Chériaux, A Sutter… - …, 2023 - Wiley Online Library
Photodynamic therapy (PDT) is a photochemistry‐based medical treatment combining light
at a specific wavelength and a photosensitizer (PS) in the presence of oxygen. Application of …

Fluorescent pH‐Responsive Probes Based on Water‐Soluble Boron‐Dipyrromethene (BODIPY) Derivatives, Featuring Long‐Wavelength Emission

A Sutter, M Elhabiri, G Ulrich - Chemistry–A European Journal, 2018 - Wiley Online Library
We describe here the synthesis of water‐soluble red/NIR‐emissive, boron‐dipyrromethene (BODIPY)
derivatives displaying optical (absorption and emission) responses in pH range of …

Carborane-Bodipy scaffolds for through space energy transfer

…, G Ulrich, JH Olivier, T Bura, A Sutter - Chemical …, 2010 - pubs.rsc.org
Use of a closo-1,12-dicarbadecaborane backbone to link two different organic dyes separated
by ca. 37 Å promotes exclusive through space electronic energy transfer with an efficiency …

Mechanistic insights into the protective roles of polyphosphate against amyloid cytotoxicity

…, E Tse, JA Lauer, MI Ivanova, A Sutter… - Life science …, 2019 - life-science-alliance.org
The universally abundant polyphosphate (polyP) accelerates fibril formation of disease-related
amyloids and protects against amyloid cytotoxicity. To gain insights into the mechanism(s…

Cross-conjugated BODIPY pigment for highly efficient dye sensitized solar cells

MF Shah, A Mirloup, TH Chowdhury, A Sutter… - Sustainable Energy & …, 2020 - pubs.rsc.org
In this study, we report a new BODIPY-based design, called the cross-conjugated design,
that takes advantage of the α- and β-position functionalization of the BODIPY core. After …

[HTML][HTML] Shared and divergent phase separation and aggregation properties of brain-expressed ubiquilins

JE Gerson, H Linton, J Xing, AB Sutter, FS Kakos… - Scientific reports, 2021 - nature.com
The brain-expressed ubiquilins, UBQLNs 1, 2 and 4, are highly homologous proteins that
participate in multiple aspects of protein homeostasis and are implicated in neurodegenerative …

Versatile synthesis of α-fused BODIPY displaying intense absorption in the NIR region and high electron affinity

Q Huaulmé, A Sutter, S Fall, D Jacquemin… - Journal of Materials …, 2018 - pubs.rsc.org
We report the design and highly efficient and versatile synthesis of four isomers of α-fused
boron dipyrromethene (BODIPY). Structure–property relationships have been established …