[PDF][PDF] Atypical acute myeloid leukemia-specific transcripts generate shared and immunogenic MHC class-I-associated epitopes
…, C Thériault, C Rulleau, J Lanoix, E Bonneil, A Feghaly… - Immunity, 2021 - cell.com
Acute myeloid leukemia (AML) has not benefited from innovative immunotherapies, mainly
because of the lack of actionable immune targets. Using an original proteogenomic approach…
because of the lack of actionable immune targets. Using an original proteogenomic approach…
[HTML][HTML] Integrated neural dynamics of sensorimotor decisions and actions
Recent theoretical models suggest that deciding about actions and executing them are not
implemented by completely distinct neural mechanisms but are instead two modes of an …
implemented by completely distinct neural mechanisms but are instead two modes of an …
[HTML][HTML] Apoptotic endothelial cells release small extracellular vesicles loaded with immunostimulatory viral-like RNAs
MP Hardy, É Audemard, F Migneault, A Feghaly… - Scientific reports, 2019 - nature.com
Endothelial cells have multifaceted interactions with the immune system, both as initiators
and targets of immune responses. In vivo, apoptotic endothelial cells release two types of …
and targets of immune responses. In vivo, apoptotic endothelial cells release two types of …
[HTML][HTML] UM171 expansion of cord blood improves donor availability and HLA matching for all patients, including minorities
M Dumont-Lagacé, A Feghaly, MC Meunier… - … and Cellular Therapy, 2022 - Elsevier
Cord blood (CB) stem cell transplantation offers a greater tolerance to HLA mismatches
compared to adult-derived stem cell transplants (ie, bone marrow or peripheral blood stem cells). …
compared to adult-derived stem cell transplants (ie, bone marrow or peripheral blood stem cells). …
Targeted variant detection using unaligned RNA-Seq reads
EO Audemard, P Gendron, A Feghaly… - Life Science …, 2019 - life-science-alliance.org
Mutations identified in acute myeloid leukemia patients are useful for prognosis and for selecting
targeted therapies. Detection of such mutations using next-generation sequencing data …
targeted therapies. Detection of such mutations using next-generation sequencing data …
Unified neural dynamics of decisions and actions in the cerebral cortex and basal ganglia
Several theoretical models suggest that deciding about actions and executing them are not
completely distinct neural mechanisms but instead two modes of an integrated dynamical …
completely distinct neural mechanisms but instead two modes of an integrated dynamical …
The sequence features that define efficient and specific hAGO2-dependent miRNA silencing guides
…, J Quenneville, J Robitaille, A Feghaly… - Nucleic acids …, 2018 - academic.oup.com
MicroRNAs (miRNAs) are ribonucleic acids (RNAs) of ∼21 nucleotides that interfere with
the translation of messenger RNAs (mRNAs) and play significant roles in development and …
the translation of messenger RNAs (mRNAs) and play significant roles in development and …
L‐n‐acetyl‐cysteine protection against cisplatin‐induced auditory neuronal and hair cell toxicity
JG Feghali, W Liu, TR Van De Water - The Laryngoscope, 2001 - Wiley Online Library
Objectives The aim of this study is to determine the efficacy of L‐N‐acetyl‐cysteine (L‐NAC)
as a protectant for inner ear auditory sensory cells against the toxic effects of cisplatin. Study …
as a protectant for inner ear auditory sensory cells against the toxic effects of cisplatin. Study …
Long-term severe hypoxia adaptation induces non-canonical EMT and a novel Wilms Tumor 1 (WT1) isoform.
E Gagnon, J Quenneville, A Feghaly, M Tual, F Major - 2023 - researchsquare.com
The majority of cancer deaths are caused by solid tumors, where the four most prevalent
cancers (breast, lung, colorectal and prostate) account for more than 60% of all cases (1). …
cancers (breast, lung, colorectal and prostate) account for more than 60% of all cases (1). …
[HTML][HTML] CAMAP: Artificial neural networks unveil the role of codon arrangement in modulating MHC-I peptides presentation
T Daouda, M Dumont-Lagacé, A Feghaly… - PLoS Computational …, 2021 - journals.plos.org
MHC-I associated peptides (MAPs) play a central role in the elimination of virus-infected and
neoplastic cells by CD8 T cells. However, accurately predicting the MAP repertoire remains …
neoplastic cells by CD8 T cells. However, accurately predicting the MAP repertoire remains …