Five enantiomeric pairs of palladium complexes of 1,2,4-triazole-derived chiral N-heterocyclic
carbene ligands were investigated to probe the influence of chirality on the compound’s …

Cell death, survival, or growth decisions in T-cell subsets depend on interplay between
cytokine-dependent and metabolic processes. The metabolic requirements of T-regulatory cells (…

Twenty-three combretastatin A-4 (CA-4) analogues were synthesized by judiciously
incorporating a functional N-heterocyclic motif present in Celecoxib (a marketed drug) while …

Throughout pregnancy, the mother's nutritional and mental health significantly influences the
kid's longterm growth and wellness. This review's objective is to provide a comprehensive …

Understanding the mechanism of resistance to tubulin-targeted anticancer drugs is
important for improved chemotherapy. In this work, a colchicine-resistant MCF-7 cell line (MCF-7 …

Polo-like kinase 1 (Plk1) is a mitotic serine/threonine kinase implicated in spindle formation
and cytokinesis in mammalian cells. Here, purified Plk1 was found to bind to reconstituted …

Molecular hydrogels represent a fascinating area of research that has its roots in drug delivery.
However, now molecular hydrogels play an intrinsic role in a multitude of applications in …

We investigated the role of a spindle assembly checkpoint protein, BubR1, in determining
the mechanism of cell killing of an anti-microtubule agent CXI-benzo-84. CXI-benzo-84 …

It is increasingly clear that cell death, survival or growth decisions of T lymphocyte subsets
depend on interplay between cytokine-dependent and metabolic processes. What the …

In the present study, microbiological quality of biscuits from street side bakery shops at
Dehardun city, India was conducted. A total 11 samples of bakery biscuits were collected …