[HTML][HTML] Shedding of viable SARS-CoV-2 after immunosuppressive therapy for cancer
…, H van Bakel, J Aberg, A García-Sastre… - New England journal …, 2020 - Mass Medical Soc
… García-Sastre) from Mount Sinai Philanthropy, awards (S10OD018522 and S10OD026880)
from the NIH Office of Research Infrastructure Programs, and a Robin Chemers Neustein …
from the NIH Office of Research Infrastructure Programs, and a Robin Chemers Neustein …
[HTML][HTML] A serological assay to detect SARS-CoV-2 seroconversion in humans
…, PL Felgner, T Moran, A García-Sastre… - Nature medicine, 2020 - nature.com
Here, we describe a serological enzyme-linked immunosorbent assay for the screening and
identification of human SARS-CoV-2 seroconverters. This assay does not require the …
identification of human SARS-CoV-2 seroconverters. This assay does not require the …
[HTML][HTML] SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters
…, RJ Webby, RA Seder, MS Suthar, A García-Sastre… - Nature, 2022 - nature.com
The recent emergence of B.1.1.529, the Omicron variant 1 , 2 , has raised concerns of
escape from protection by vaccines and therapeutic antibodies. A key test for potential …
escape from protection by vaccines and therapeutic antibodies. A key test for potential …
[HTML][HTML] A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
A newly described coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
which is the causative agent of coronavirus disease 2019 (COVID-19), has …
which is the causative agent of coronavirus disease 2019 (COVID-19), has …
Type 1 interferons and the virus-host relationship: a lesson in detente
A García-Sastre, CA Biron - Science, 2006 - science.org
The interface between an infectious agent and its host represents the ultimate battleground
for survival: The microbe must secure a niche for replication, whereas the host must limit the …
for survival: The microbe must secure a niche for replication, whereas the host must limit the …
Rescue of influenza A virus from recombinant DNA
…, P Palese, GG Brownlee, A García-Sastre - Journal of …, 1999 - Am Soc Microbiol
We have rescued influenza A virus by transfection of 12 plasmids into Vero cells. The eight
individual negative-sense genomic viral RNAs were transcribed from plasmids containing …
individual negative-sense genomic viral RNAs were transcribed from plasmids containing …
Inborn errors of type I IFN immunity in patients with life-threatening COVID-19
…, A Amara, M Nussenzweig, A García-Sastre… - Science, 2020 - science.org
INTRODUCTION Clinical outcomes of human severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) infection range from silent infection to lethal coronavirus disease 2019 (…
2 (SARS-CoV-2) infection range from silent infection to lethal coronavirus disease 2019 (…
[PDF][PDF] Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes
…, M Tanaka, N van Rooijen, A García-Sastre… - Immunity, 2013 - cell.com
Despite accumulating evidence suggesting local self-maintenance of tissue macrophages
in the steady state, the dogma remains that tissue macrophages derive from monocytes. …
in the steady state, the dogma remains that tissue macrophages derive from monocytes. …
Distinct RIG-I and MDA5 signaling by RNA viruses in innate immunity
…, S Akira, MA Gill, A García-Sastre… - Journal of …, 2008 - Am Soc Microbiol
Alpha/beta interferon immune defenses are essential for resistance to viruses and can be
triggered through the actions of the cytoplasmic helicases retinoic acid-inducible gene I (RIG-I) …
triggered through the actions of the cytoplasmic helicases retinoic acid-inducible gene I (RIG-I) …
[HTML][HTML] Animal models for COVID-19
…, M Beer, T Brasel, JFW Chan, A García-Sastre… - Nature, 2020 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the aetiological agent of
coronavirus disease 2019 (COVID-19), an emerging respiratory infection caused by the …
coronavirus disease 2019 (COVID-19), an emerging respiratory infection caused by the …