[HTML][HTML] Multiple roles of the capsid protein in the early steps of HIV-1 infection
A Fassati - Virus research, 2012 - Elsevier
The early steps of HIV-1 infection starting after virus entry into cells up to integration of its
genome into host chromosomes are poorly understood. From seminal work showing that HIV-1 …
genome into host chromosomes are poorly understood. From seminal work showing that HIV-1 …
Characterization of intracellular reverse transcription complexes of human immunodeficiency virus type 1
To examine the early events of the life cycle of human immunodeficiency virus type 1 (HIV-1),
we analyzed the intracellular complexes mediating reverse transcription isolated from …
we analyzed the intracellular complexes mediating reverse transcription isolated from …
Transmissible dog cancer genome reveals the origin and history of an ancient cell lineage
…, AB De Nardi, EM Donelan, G Marino, A Fassati… - Science, 2014 - science.org
Canine transmissible venereal tumor (CTVT) is the oldest known somatic cell lineage. It is a
transmissible cancer that propagates naturally in dogs. We sequenced the genomes of two …
transmissible cancer that propagates naturally in dogs. We sequenced the genomes of two …
Nuclear import of viral DNA genomes
The genomes of many viruses traffic into the nucleus, where they are either integrated into
host chromosomes or maintained as episomal DNA and then transcriptionally activated or …
host chromosomes or maintained as episomal DNA and then transcriptionally activated or …
[HTML][HTML] Clonal origin and evolution of a transmissible cancer
C Murgia, JK Pritchard, SY Kim, A Fassati, RA Weiss - Cell, 2006 - cell.com
The transmissible agent causing canine transmissible venereal tumor (CTVT) is thought to
be the tumor cell itself. To test this hypothesis, we analyzed genetic markers including major …
be the tumor cell itself. To test this hypothesis, we analyzed genetic markers including major …
[HTML][HTML] HIV infection of non-dividing cells: a divisive problem
A Fassati - Retrovirology, 2006 - Springer
Understanding how lentiviruses can infect terminally differentiated, non-dividing cells has
proven a very complex and controversial problem. It is, however, a problem worth investigating…
proven a very complex and controversial problem. It is, however, a problem worth investigating…
[HTML][HTML] Impact of COVID-19 lockdown on sleep quality in university students and administration staff
Introduction In Italy, lockdown due to COVID-19 health emergency started on March 10 and
partially ended on May 3rd, 2020. There was a significant increase of psychological distress …
partially ended on May 3rd, 2020. There was a significant increase of psychological distress …
[HTML][HTML] Nuclear import of HIV-1 intracellular reverse transcription complexes is mediated by importin 7
Human immunodeficiency virus type 1 (HIV-1), like other lentiviruses, can infect non-dividing
cells. This property depends on the active nuclear import of its intracellular reverse …
cells. This property depends on the active nuclear import of its intracellular reverse …
Structural basis for nuclear import of splicing factors by human Transportin 3
…, VN KewalRamani, A Fassati… - Proceedings of the …, 2014 - National Acad Sciences
Transportin 3 (Tnpo3, Transportin-SR2) is implicated in nuclear import of splicing factors
and HIV-1 replication. Herein, we show that the majority of cellular Tnpo3 binding partners …
and HIV-1 replication. Herein, we show that the majority of cellular Tnpo3 binding partners …
[HTML][HTML] Evolution of enhanced innate immune evasion by SARS-CoV-2
The emergence of SARS-CoV-2 variants of concern suggests viral adaptation to enhance
human-to-human transmission 1 , 2 . Although much effort has focused on the characterization …
human-to-human transmission 1 , 2 . Although much effort has focused on the characterization …