User profiles for A. Bruckbauer

Andreas Bruckbauer

CRUK Cambridge Institute, University of Cambridge
Verified email at cruk.cam.ac.uk
Cited by 5055

[PDF][PDF] The membrane skeleton controls diffusion dynamics and signaling through the B cell receptor

…, P Barral, M Weber, O Dushek, A Bruckbauer… - Immunity, 2010 - cell.com
Early events of B cell activation after B cell receptor (BCR) triggering have been well
characterized. However, little is known about the steady state of the BCR on the cell surface. Here, …

[PDF][PDF] The actin and tetraspanin networks organize receptor nanoclusters to regulate B cell receptor-mediated signaling

…, KL Otipoby, R Carter, LB Justement, A Bruckbauer… - Immunity, 2013 - cell.com
A key role is emerging for the cytoskeleton in coordinating receptor signaling, although the
underlying molecular requirements remain unclear. Here we show that cytoskeleton …

[PDF][PDF] Initiation of antiviral B cell immunity relies on innate signals from spatially positioned NKT cells

…, RP Sekaly, DH Barouch, AK Shalek, A Bruckbauer… - Cell, 2018 - cell.com
B cells constitute an essential line of defense from pathogenic infections through the
generation of class-switched antibody-secreting cells (ASCs) in germinal centers. Although this …

CD169+ macrophages present lipid antigens to mediate early activation of iNKT cells in lymph nodes

P Barral, P Polzella, A Bruckbauer, N Van Rooijen… - Nature …, 2010 - nature.com
Invariant natural killer T cells (iNKT cells) are involved in the host defense against microbial
infection. Although it is known that iNKT cells recognize glycolipids presented by CD1d, how …

Supramolecular organization of the sperm plasma membrane during maturation and capacitation

…, PS James, L Howes, A Bruckbauer… - Asian journal of …, 2007 - Wiley Online Library
Aim: In the present study, a variety of high resolution microscopy techniques were used to
visualize the organization and motion of lipids and proteins in the sperm's plasma membrane. …

On the chloride activation in SERS and single molecule SERS

A Otto, A Bruckbauer, YX Chen - Journal of molecular structure, 2003 - Elsevier
In ‘common (canonical)’ multi-adsorbate, multi-particle surface enhanced Raman scattering
(SERS) the vibrational band intensities of adsorbates at roughened electrodes and at …

Dynamic cortical actin remodeling by ERM proteins controls BCR microcluster organization and integrity

B Treanor, D Depoil, A Bruckbauer… - Journal of Experimental …, 2011 - rupress.org
Signaling microclusters are a common feature of lymphocyte activation. However, the
mechanisms controlling the size and organization of these discrete structures are poorly …

STRIPAK components determine mode of cancer cell migration and metastasis

CD Madsen, S Hooper, M Tozluoglu, A Bruckbauer… - Nature cell …, 2015 - nature.com
The contractile actomyosin cytoskeleton and its connection to the plasma membrane are critical
for control of cell shape and migration. We identify three STRIPAK complex components, …

Asymmetric segregation of polarized antigen on B cell division shapes presentation capacity

…, N Martinez-Martin, NE Harwood, A Bruckbauer… - Science, 2012 - science.org
During the activation of humoral immune responses, B cells acquire antigen for subsequent
presentation to cognate T cells. Here we show that after mouse B cells accumulate antigen, …

[HTML][HTML] Synergistic effects of leucine and resveratrol on insulin sensitivity and fat metabolism in adipocytes and mice

A Bruckbauer, MB Zemel, T Thorpe, MR Akula… - Nutrition & …, 2012 - Springer
Background Sirtuins are important regulators of glucose and fat metabolism, and sirtuin
activation has been proposed as a therapeutic target for insulin resistance and diabetes. We …