Cells have developed highly sophisticated ways to accurately pass on their genetic information
to the daughter cells. In animal cells, which undergo open mitosis, the nuclear envelope …

The role of cytosolic stress granules in the integrated stress response has remained largely
enigmatic. Here, we studied the functionality of the ubiquitin‐proteasome system (UPS) in …

Chromatin undergoes extensive structural changes during the cell cycle. Upon mitotic entry,
metazoan chromatin undergoes tremendous condensation, creating mitotic chromosomes …

Amyloid fibrils are mechanically robust and partly resistant to proteolytic degradation, making
them potential candidates for scaffold materials in cell culture, tissue engineering, drug …

The mitotic spindle, essential for segregating the sister chromatids into the two evolving
daughter cells, is composed of highly dynamic cytoskeletal filaments, the microtubules. The …

The eukaryotic nucleus remodels extensively during mitosis. Upon mitotic entry, the nuclear
envelope breaks down and chromosomes condense into rod-shaped bodies, which are …

RecQ-like helicase 4 (RECQL4) is mutated in patients suffering from the Rothmund–Thomson
syndrome, a genetic disease characterized by premature aging, skeletal malformations, …

Due to the inherent toxicity of protein aggregates, the propensity of natural, functional
amyloidogenic proteins to aggregate must be tightly controlled to avoid negative consequences on …

… Laser ablation of a k-fiber and consequent movement of the kinetochore that was separated
from the pole showed that the bridging fiber, the intact sister kinetochore fiber and the …

During the vertebrate cell cycle chromatin undergoes extensive structural and functional
changes. Upon mitotic entry, it massively condenses into rod shaped chromosomes which are …