|
| Status |
Public on Jul 01, 2016 |
| Title |
Gene expression data from Duchenne muscular dystrophy patients versus controls |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
gene expression data is from RNA extracted from muscle biopsy samples taken from boys with Duchenne muscular dystrophy (DMD) or pathologically normal controls (CTRL). Each muscle biospy was examined in detail histologically by Dr. Eric P. Hoffman at Children's National Medical Center to determine stage of disease. In addition, the absence or presence of dystrophin was determined via western blot analyses.
We utilized Human U133 2.0 arrays to examine the transcriptome of each muscle, and then we compared differential gene expression between DMD patient muscles and CTRL muscules. We set the FDR p value for significance at 0.05 and at least a 1.5 fold difference in DMD/CTRL
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| |
|
| Overall design |
compared differential gene exrpression between DMD versus Control
|
| |
|
| Contributor(s) |
Dorsey SG, Ward CW |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Jun 01, 2012 |
| Last update date |
Dec 09, 2019 |
| Contact name |
Susan G Dorsey |
| E-mail(s) |
sdorsey@son.umaryland.edu
|
| Organization name |
University of Maryland Baltimore
|
| Department |
Pain and Translational Symptom Science
|
| Street address |
655 West Lombard Street
|
| City |
Baltimore |
| ZIP/Postal code |
21201 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
|
| Samples (22)
|
|
| Relations |
| BioProject |
PRJNA167804 |
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