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| Status |
Public on Feb 11, 2011 |
| Title |
Genome-wide gene expression profiling on pre-chemotherapy biopsies of osteosarcoma patients who developed metastases within 5yrs (n=34) and patients who did not develop metastases within 5yrs (n=19) |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
High-grade osteosarcoma is a malignant primary bone tumor with a peak incidence in puberty. Overall survival of patients with metastatic disease is approximately twenty percent. Mechanisms behind the development of metastases in osteosarcoma are unknown. To identify gene signatures that play a role in metastasis, we performed genome-wide gene expression profiling on pre-chemotherapy biopsies of osteosarcoma patients who developed metastases within 5yrs and patients who did not develop metastases within 5yrs.
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| Overall design |
Pre-chemotherapy biopsies of osteosarcoma patients who developed metastases within 5yrs (n=34) were compared with pre-chemotherapy biopsies of osteosarcoma patients who did not develop metastases within 5yrs (n=19).
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| Citation(s) |
21372215 |
| Submission date |
Apr 08, 2010 |
| Last update date |
Mar 22, 2012 |
| Contact name |
Marieke Lydia Kuijjer |
| Organization name |
Centre for Molecular Medicine Norway
|
| Lab |
Kuijjer
|
| Street address |
Gaustadalléen 21
|
| City |
Oslo |
| ZIP/Postal code |
0349 |
| Country |
Norway |
| |
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| Platforms (1) |
| GPL10295 |
Illumina human-6 v2.0 expression beadchip (using nuIDs as identifier) |
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| Samples (53)
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| Relations |
| BioProject |
PRJNA126279 |
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