|
| Status |
Public on Oct 03, 2018 |
| Title |
Kinetic analysis of TGFbeta-induced EMT in NMuMG/E9 cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
To investigate the transcriptional remodelling during EMT, we treated normal murine mammary gland epithelial cells with TGFbeta for 0, 2h, 6h, 12h, 24h, 36h, 48h, 60h, 72h, 96h, 168h and 240h. Using WGCNA and pathway enrichment analysis we identified multiple gene expression modules that were enriched in general, signaling, metabolic or stuctural pathways highly relevant for EMT.
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| |
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| Overall design |
RNA sequencing of NMuMG/E9 cells induced to undergo EMT by treatment with TGFbeta from 0-10 days.
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| |
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| Contributor(s) |
Saxena M, Meyer-Schaller N, Ivanek R, Christofori G |
| Citation(s) |
30108334 |
| Submission date |
Apr 06, 2018 |
| Last update date |
Nov 17, 2021 |
| Contact name |
DBM Bioinformatics Core Facility |
| Phone |
+41612073541
|
| Organization name |
University of Basel
|
| Department |
Departement of Biomedicine
|
| Street address |
Hebelstrasse 20
|
| City |
Basel |
| State/province |
BS |
| ZIP/Postal code |
4053 |
| Country |
Switzerland |
| |
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| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
|
| Samples (24)
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| This SubSeries is part of SuperSeries: |
| GSE115376 |
Transcription (co)factor and miRNA regulatory landscape of EMT |
|
| Relations |
| BioProject |
PRJNA449023 |
| SRA |
SRP137808 |
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