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2017 4
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2021 5
2022 3
2024 1

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Page 1
Improving sampling of crystallographic disorder in ensemble refinement.
Ploscariu N, Burnley T, Gros P, Pearce NM. Ploscariu N, et al. Among authors: pearce nm. Acta Crystallogr D Struct Biol. 2021 Nov 1;77(Pt 11):1357-1364. doi: 10.1107/S2059798321010044. Epub 2021 Oct 20. Acta Crystallogr D Struct Biol. 2021. PMID: 34726164 Free PMC article.
Covalent bicyclization of protein complexes yields durable quaternary structures.
Hutchins GH, Kiehstaller S, Poc P, Lewis AH, Oh J, Sadighi R, Pearce NM, Ibrahim M, Drienovská I, Rijs AM, Neubacher S, Hennig S, Grossmann TN. Hutchins GH, et al. Among authors: pearce nm. Chem. 2024 Feb 8;10(2):615-627. doi: 10.1016/j.chempr.2023.10.003. Chem. 2024. PMID: 38344167 Free PMC article.
Achieving Efficient Fragment Screening at XChem Facility at Diamond Light Source.
Douangamath A, Powell A, Fearon D, Collins PM, Talon R, Krojer T, Skyner R, Brandao-Neto J, Dunnett L, Dias A, Aimon A, Pearce NM, Wild C, Gorrie-Stone T, von Delft F. Douangamath A, et al. Among authors: pearce nm. J Vis Exp. 2021 May 29;(171). doi: 10.3791/62414. J Vis Exp. 2021. PMID: 34125095
Bicyclic β-Sheet Mimetics that Target the Transcriptional Coactivator β-Catenin and Inhibit Wnt Signaling.
Wendt M, Bellavita R, Gerber A, Efrém NL, van Ramshorst T, Pearce NM, Davey PRJ, Everard I, Vazquez-Chantada M, Chiarparin E, Grieco P, Hennig S, Grossmann TN. Wendt M, et al. Among authors: pearce nm. Angew Chem Int Ed Engl. 2021 Jun 14;60(25):13937-13944. doi: 10.1002/anie.202102082. Epub 2021 May 5. Angew Chem Int Ed Engl. 2021. PMID: 33783110 Free PMC article.
Mechanistic insights into the C55-P targeting lipopeptide antibiotics revealed by structure-activity studies and high-resolution crystal structures.
Wood TM, Zeronian MR, Buijs N, Bertheussen K, Abedian HK, Johnson AV, Pearce NM, Lutz M, Kemmink J, Seirsma T, Hamoen LW, Janssen BJC, Martin NI. Wood TM, et al. Among authors: pearce nm. Chem Sci. 2022 Feb 21;13(10):2985-2991. doi: 10.1039/d1sc07190d. eCollection 2022 Mar 9. Chem Sci. 2022. PMID: 35382464 Free PMC article.
16 results