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Page 1
The Coenzyme A Level Modulator Hopantenate (HoPan) Inhibits Phosphopantotenoylcysteine Synthetase Activity.
ACS Chem Biol. 2021 Nov 19;16(11):2401-2414. doi: 10.1021/acschembio.1c00535. Epub 2021 Sep 28.
ACS Chem Biol. 2021.
PMID: 34582681
Free PMC article.
Developing Pantetheinase-Resistant Pantothenamide Antibacterials: Structural Modification Impacts on PanK Interaction and Mode of Action.
Barnard L, Mostert KJ, van Otterlo WAL, Strauss E.
Barnard L, et al. Among authors: mostert kj.
ACS Infect Dis. 2018 May 11;4(5):736-743. doi: 10.1021/acsinfecdis.7b00240. Epub 2018 Jan 23.
ACS Infect Dis. 2018.
PMID: 29332383
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Vnn1 pantetheinase limits the Warburg effect and sarcoma growth by rescuing mitochondrial activity.
Giessner C, Millet V, Mostert KJ, Gensollen T, Vu Manh TP, Garibal M, Dieme B, Attaf-Bouabdallah N, Chasson L, Brouilly N, Laprie C, Lesluyes T, Blay JY, Shintu L, Martin JC, Strauss E, Galland F, Naquet P.
Giessner C, et al. Among authors: mostert kj.
Life Sci Alliance. 2018 Jul 23;1(4):e201800073. doi: 10.26508/lsa.201800073. eCollection 2018 Aug.
Life Sci Alliance. 2018.
PMID: 30456364
Free PMC article.
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Overcoming synthetic challenges in targeting coenzyme A biosynthesis with the antimicrobial natural product CJ-15,801.
Domingo R, van der Westhuyzen R, Hamann AR, Mostert KJ, Barnard L, Paquet T, Tjhin ET, Saliba KJ, van Otterlo WAL, Strauss E.
Domingo R, et al. Among authors: mostert kj.
Medchemcomm. 2019 Oct 17;10(12):2118-2125. doi: 10.1039/c9md00312f. eCollection 2019 Dec 1.
Medchemcomm. 2019.
PMID: 32206243
Free PMC article.
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