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PIM1 controls GBP1 activity to limit self-damage and to guard against pathogen infection.
Fisch D, Pfleiderer MM, Anastasakou E, Mackie GM, Wendt F, Liu X, Clough B, Lara-Reyna S, Encheva V, Snijders AP, Bando H, Yamamoto M, Beggs AD, Mercer J, Shenoy AR, Wollscheid B, Maslowski KM, Galej WP, Frickel EM. Fisch D, et al. Among authors: mackie gm. Science. 2023 Oct 6;382(6666):eadg2253. doi: 10.1126/science.adg2253. Epub 2023 Oct 6. Science. 2023. PMID: 37797010 Free PMC article.
LRR-protein RNH1 dampens the inflammasome activation and is associated with COVID-19 severity.
Bombaci G, Sarangdhar MA, Andina N, Tardivel A, Yu EC, Mackie GM, Pugh M, Ozan VB, Banz Y, Spinetti T, Hirzel C, Youd E, Schefold JC, Taylor G, Gazdhar A, Bonadies N, Angelillo-Scherrer A, Schneider P, Maslowski KM, Allam R. Bombaci G, et al. Among authors: mackie gm. Life Sci Alliance. 2022 Mar 7;5(6):e202101226. doi: 10.26508/lsa.202101226. Print 2022 Jun. Life Sci Alliance. 2022. PMID: 35256513 Free PMC article.
Nur77-Tempo mice reveal T cell steady state antigen recognition.
Elliot TAE, Jennings EK, Lecky DAJ, Rouvray S, Mackie GM, Scarfe L, Sheriff L, Ono M, Maslowski KM, Bending D. Elliot TAE, et al. Among authors: mackie gm. Discov Immunol. 2022 Dec 22;1(1):kyac009. doi: 10.1093/discim/kyac009. Discov Immunol. 2022. PMID: 36704407 Free PMC article.