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Interleukin-10 receptor signaling promotes the maintenance of a PD-1int TCF-1+ CD8+ T cell population that sustains anti-tumor immunity.
Hanna BS, Llaó-Cid L, Iskar M, Roessner PM, Klett LC, Wong JKL, Paul Y, Ioannou N, Öztürk S, Mack N, Kalter V, Colomer D, Campo E, Bloehdorn J, Stilgenbauer S, Dietrich S, Schmidt M, Gabriel R, Rippe K, Feuerer M, Ramsay AG, Lichter P, Zapatka M, Seiffert M. Hanna BS, et al. Among authors: klett lc. Immunity. 2021 Dec 14;54(12):2825-2841.e10. doi: 10.1016/j.immuni.2021.11.004. Epub 2021 Dec 7. Immunity. 2021. PMID: 34879221 Free article.
Nucleosome repositioning in chronic lymphocytic leukemia.
Piroeva KV, McDonald C, Xanthopoulos C, Fox C, Clarkson CT, Mallm JP, Vainshtein Y, Ruje L, Klett LC, Stilgenbauer S, Mertens D, Kostareli E, Rippe K, Teif VB. Piroeva KV, et al. Among authors: klett lc. Genome Res. 2023 Oct;33(10):1649-1661. doi: 10.1101/gr.277298.122. Epub 2023 Sep 12. Genome Res. 2023. PMID: 37699659 Free PMC article.
Linking aberrant chromatin features in chronic lymphocytic leukemia to transcription factor networks.
Mallm JP, Iskar M, Ishaque N, Klett LC, Kugler SJ, Muino JM, Teif VB, Poos AM, Großmann S, Erdel F, Tavernari D, Koser SD, Schumacher S, Brors B, König R, Remondini D, Vingron M, Stilgenbauer S, Lichter P, Zapatka M, Mertens D, Rippe K. Mallm JP, et al. Among authors: klett lc. Mol Syst Biol. 2019 May 22;15(5):e8339. doi: 10.15252/msb.20188339. Mol Syst Biol. 2019. PMID: 31118277 Free PMC article.
Methylome-based cell-of-origin modeling (Methyl-COOM) identifies aberrant expression of immune regulatory molecules in CLL.
Wierzbinska JA, Toth R, Ishaque N, Rippe K, Mallm JP, Klett LC, Mertens D, Zenz T, Hielscher T, Seifert M, Küppers R, Assenov Y, Lutsik P, Stilgenbauer S, Roessner PM, Seiffert M, Byrd J, Oakes CC, Plass C, Lipka DB. Wierzbinska JA, et al. Among authors: klett lc. Genome Med. 2020 Mar 18;12(1):29. doi: 10.1186/s13073-020-00724-7. Genome Med. 2020. PMID: 32188505 Free PMC article.