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Mechanical disengagement of the cohesin ring.
Richeldi M, Pobegalov G, Higashi TL, Gmurczyk K, Uhlmann F, Molodtsov MI. Richeldi M, et al. Among authors: higashi tl. Nat Struct Mol Biol. 2024 Jan;31(1):23-31. doi: 10.1038/s41594-023-01122-4. Epub 2023 Oct 23. Nat Struct Mol Biol. 2024. PMID: 37872232
SMC complexes: Lifting the lid on loop extrusion.
Higashi TL, Uhlmann F. Higashi TL, et al. Curr Opin Cell Biol. 2022 Feb;74:13-22. doi: 10.1016/j.ceb.2021.12.003. Epub 2022 Jan 8. Curr Opin Cell Biol. 2022. PMID: 35016058 Free PMC article. Review.
A Structure-Based Mechanism for DNA Entry into the Cohesin Ring.
Higashi TL, Eickhoff P, Sousa JS, Locke J, Nans A, Flynn HR, Snijders AP, Papageorgiou G, O'Reilly N, Chen ZA, O'Reilly FJ, Rappsilber J, Costa A, Uhlmann F. Higashi TL, et al. Mol Cell. 2020 Sep 17;79(6):917-933.e9. doi: 10.1016/j.molcel.2020.07.013. Epub 2020 Aug 4. Mol Cell. 2020. PMID: 32755595 Free PMC article.
In vitro loading of human cohesin on DNA by the human Scc2-Scc4 loader complex.
Bermudez VP, Farina A, Higashi TL, Du F, Tappin I, Takahashi TS, Hurwitz J. Bermudez VP, et al. Among authors: higashi tl. Proc Natl Acad Sci U S A. 2012 Jun 12;109(24):9366-71. doi: 10.1073/pnas.1206840109. Epub 2012 May 24. Proc Natl Acad Sci U S A. 2012. PMID: 22628566 Free PMC article.