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Page 1
Hemagglutinins of Avian Influenza Viruses Are Proteolytically Activated by TMPRSS2 in Human and Murine Airway Cells.
J Virol. 2021 Sep 27;95(20):e0090621. doi: 10.1128/JVI.00906-21. Epub 2021 Jul 28.
J Virol. 2021.
PMID: 34319155
Free PMC article.
TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells.
Bestle D, Heindl MR, Limburg H, Van Lam van T, Pilgram O, Moulton H, Stein DA, Hardes K, Eickmann M, Dolnik O, Rohde C, Klenk HD, Garten W, Steinmetzer T, Böttcher-Friebertshäuser E.
Bestle D, et al.
Life Sci Alliance. 2020 Jul 23;3(9):e202000786. doi: 10.26508/lsa.202000786. Print 2020 Sep.
Life Sci Alliance. 2020.
PMID: 32703818
Free PMC article.
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TMPRSS2 Is the Major Activating Protease of Influenza A Virus in Primary Human Airway Cells and Influenza B Virus in Human Type II Pneumocytes.
Limburg H, Harbig A, Bestle D, Stein DA, Moulton HM, Jaeger J, Janga H, Hardes K, Koepke J, Schulte L, Koczulla AR, Schmeck B, Klenk HD, Böttcher-Friebertshäuser E.
Limburg H, et al. Among authors: bestle d.
J Virol. 2019 Oct 15;93(21):e00649-19. doi: 10.1128/JVI.00649-19. Print 2019 Nov 1.
J Virol. 2019.
PMID: 31391268
Free PMC article.
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ACE2 acts as a novel regulator of TMPRSS2-catalyzed proteolytic activation of influenza A virus in airway cells.
Heindl MR, Rupp A-L, Schwerdtner M, Bestle D, Harbig A, De Rocher A, Schmacke LC, Staker B, Steinmetzer T, Stein DA, Moulton HM, Böttcher-Friebertshäuser E.
Heindl MR, et al. Among authors: bestle d.
J Virol. 2024 Mar 12:e0010224. doi: 10.1128/jvi.00102-24. Online ahead of print.
J Virol. 2024.
PMID: 38470058
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