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Cancer lineage-specific regulation of YAP responsive elements revealed through large-scale functional epigenomic screens.
Barbosa IAM, Gopalakrishnan R, Mercan S, Mourikis TP, Martin T, Wengert S, Sheng C, Ji F, Lopes R, Knehr J, Altorfer M, Lindeman A, Russ C, Naumann U, Golji J, Sprouffske K, Barys L, Tordella L, Schübeler D, Schmelzle T, Galli GG. Barbosa IAM, et al. Among authors: altorfer m. Nat Commun. 2023 Jul 3;14(1):3907. doi: 10.1038/s41467-023-39527-w. Nat Commun. 2023. PMID: 37400441 Free PMC article.
Protein destabilization underlies pathogenic missense mutations in ARID1B.
Mermet-Meillon F, Mercan S, Bauer-Probst B, Allard C, Bleu M, Calkins K, Knehr J, Altorfer M, Naumann U, Sprouffske K, Barys L, Sesterhenn F, Galli GG. Mermet-Meillon F, et al. Among authors: altorfer m. Nat Struct Mol Biol. 2024 Feb 12. doi: 10.1038/s41594-024-01229-2. Online ahead of print. Nat Struct Mol Biol. 2024. PMID: 38347147
Genome assembly of the bearded iris, Iris pallida Lam.
Bruccoleri RE, Oakeley EJ, Faust AME, Altorfer M, Dessus-Babus S, Burckhardt D, Oertli M, Naumann U, Petersen F, Wong J. Bruccoleri RE, et al. Among authors: altorfer m. GigaByte. 2023 Oct 5;2023:gigabyte94. doi: 10.46471/gigabyte.94. eCollection 2023. GigaByte. 2023. PMID: 37829656 Free PMC article.
Systematic dissection of transcriptional regulatory networks by genome-scale and single-cell CRISPR screens.
Lopes R, Sprouffske K, Sheng C, Uijttewaal ECH, Wesdorp AE, Dahinden J, Wengert S, Diaz-Miyar J, Yildiz U, Bleu M, Apfel V, Mermet-Meillon F, Krese R, Eder M, Olsen AV, Hoppe P, Knehr J, Carbone W, Cuttat R, Waldt A, Altorfer M, Naumann U, Weischenfeldt J, deWeck A, Kauffmann A, Roma G, Schübeler D, Galli GG. Lopes R, et al. Among authors: altorfer m. Sci Adv. 2021 Jul 2;7(27):eabf5733. doi: 10.1126/sciadv.abf5733. Print 2021 Jul. Sci Adv. 2021. PMID: 34215580 Free article.
Drug-induced chromatin accessibility changes associate with sensitivity to liver tumor promotion.
Vitobello A, Perner J, Beil J, Zhu J, Del Río-Espínola A, Morawiec L, Westphal M, Dubost V, Altorfer M, Naumann U, Mueller A, Kapur K, Borowsky M, Henderson C, Wolf CR, Schwarz M, Moggs J, Terranova R. Vitobello A, et al. Among authors: altorfer m. Life Sci Alliance. 2019 Oct 15;2(5):e201900461. doi: 10.26508/lsa.201900461. Print 2019 Oct. Life Sci Alliance. 2019. PMID: 31615920 Free PMC article.
IL-26 Potentiates Type 2 Skin Inflammation in the Presence of IL-1β.
Bier K, Senajova Z, Henrion F, Wang Y, Bruno S, Rauld C, Hörmann LC, Barske C, Delucis-Bronn C, Bergling S, Altorfer M, Hägele J, Knehr J, Junt T, Roediger B, Röhn TA, Kolbinger F. Bier K, et al. Among authors: altorfer m. J Invest Dermatol. 2024 Jan 17:S0022-202X(24)00017-4. doi: 10.1016/j.jid.2023.12.018. Online ahead of print. J Invest Dermatol. 2024. PMID: 38237730
High-resolution chemical dissection of a model eukaryote reveals targets, pathways and gene functions.
Hoepfner D, Helliwell SB, Sadlish H, Schuierer S, Filipuzzi I, Brachat S, Bhullar B, Plikat U, Abraham Y, Altorfer M, Aust T, Baeriswyl L, Cerino R, Chang L, Estoppey D, Eichenberger J, Frederiksen M, Hartmann N, Hohendahl A, Knapp B, Krastel P, Melin N, Nigsch F, Oakeley EJ, Petitjean V, Petersen F, Riedl R, Schmitt EK, Staedtler F, Studer C, Tallarico JA, Wetzel S, Fishman MC, Porter JA, Movva NR. Hoepfner D, et al. Among authors: altorfer m. Microbiol Res. 2014 Feb-Mar;169(2-3):107-20. doi: 10.1016/j.micres.2013.11.004. Epub 2013 Dec 1. Microbiol Res. 2014. PMID: 24360837 Free article.
11 results