Abstract
During the past year, the small GTP-binding proteins Rho and Rac have each been shown to regulate a signal transduction pathway linking growth factor receptors to distinct changes in the actin cytoskeleton. A number of regulatory molecules for Rho-like proteins have been identified and some of these may cross-talk with the Ras signalling pathway.
MeSH terms
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Animals
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GTP-Binding Proteins / physiology*
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GTPase-Activating Proteins*
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Guanine Nucleotide Dissociation Inhibitors*
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Humans
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Models, Biological
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Signal Transduction / physiology
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rac GTP-Binding Proteins
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rho-Specific Guanine Nucleotide Dissociation Inhibitors
Substances
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GTPase-Activating Proteins
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Guanine Nucleotide Dissociation Inhibitors
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rho GTPase-activating protein
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rho-Specific Guanine Nucleotide Dissociation Inhibitors
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GTP-Binding Proteins
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rac GTP-Binding Proteins