Abstract
The RNP domain is found in a number of proteins involved in processing and transport of mRNA precursors. The crystal structure of a complex between the U1A spliceosomal protein and its cognate RNA hairpin at 1.92 A resolution reveals the molecular basis of sequence-specific RNA recognition by the RNP domain.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Amino Acid Sequence
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Base Sequence
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Biological Transport
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Molecular Sequence Data
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Protein Structure, Tertiary*
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RNA / metabolism*
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RNA Processing, Post-Transcriptional*
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RNA-Binding Proteins / chemistry*
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Ribonucleoproteins / chemistry*
Substances
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RNA-Binding Proteins
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Ribonucleoproteins
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RNA