High incidence of RAS signalling pathway mutations in MLL-rearranged acute myeloid leukemia

Leukemia. 2013 Sep;27(9):1933-6. doi: 10.1038/leu.2013.90. Epub 2013 Mar 28.

Authors

V Grossmann, S Schnittger, F Poetzinger, A Kohlmann, A Stiel, C Eder, A Fasan, W Kern, T Haferlach, C Haferlach

PMID: 23535558
DOI: 10.1038/leu.2013.90

No abstract available

Publication types

Letter

MeSH terms

Adult
Aged
Aged, 80 and over
Chromosome Aberrations
Female
Humans
Leukemia, Myeloid, Acute / diagnosis
Leukemia, Myeloid, Acute / genetics*
Leukemia, Myeloid, Acute / metabolism*
Leukemia, Myeloid, Acute / mortality
Male
Middle Aged
Mutation*
Myeloid-Lymphoid Leukemia Protein / genetics*
Prognosis
Proto-Oncogene Proteins p21(ras) / genetics*
Proto-Oncogene Proteins p21(ras) / metabolism*
Signal Transduction*
Young Adult

Substances

Myeloid-Lymphoid Leukemia Protein
Proto-Oncogene Proteins p21(ras)