Abstract
Alu elements are primate-specific repeats and comprise 11% of the human genome. They have wide-ranging influences on gene expression. Their contribution to genome evolution, gene regulation and disease is reviewed.
Publication types
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Research Support, N.I.H., Extramural
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Review
MeSH terms
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Alu Elements / genetics*
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Animals
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Biological Evolution
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DNA Copy Number Variations
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Gene Expression Regulation*
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Genetic Variation
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Genome, Human*
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Genomic Instability
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Humans
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Mutagenesis, Insertional / genetics*
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Nucleic Acid Conformation
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Primates / genetics*
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Retroelements / genetics