Sex chromosomes: evolution of the weird and wonderful

Curr Biol. 2005 Feb 22;15(4):R129-31. doi: 10.1016/j.cub.2005.02.011.

Abstract

New findings in the platypus and Drosophila pseudoobscura illustrate, yet again, that the sex chromosomes seem never to stop evolving. Degeneration processes lead to a continual loss of genes and gene activity on the Y chromosome, and complete loss of Y-linked genes is possible if autosomal genes take over control of male fertility - though addition of new material to the sex chromosomes may start the process anew.

Publication types

  • Review

MeSH terms

  • Animals
  • Drosophila / genetics*
  • Evolution, Molecular*
  • Male
  • Models, Genetic*
  • Platypus / genetics*
  • Recombination, Genetic / genetics
  • Sex Chromosomes / genetics*
  • Transcription Factors / genetics
  • Transcription Factors / metabolism

Substances

  • DMRT1 protein
  • Transcription Factors