Opinion: Searching for the elusive targets of farnesyltransferase inhibitors

Nat Rev Cancer. 2003 Dec;3(12):945-51. doi: 10.1038/nrc1234.
No abstract available

Publication types

  • Review

MeSH terms

  • Alkyl and Aryl Transferases / antagonists & inhibitors*
  • Alkyl and Aryl Transferases / metabolism
  • Animals
  • Enzyme Inhibitors / pharmacology*
  • Farnesyltranstransferase
  • GTP-Binding Proteins / metabolism*
  • Humans
  • Neoplasms / drug therapy*
  • Neoplasms / enzymology
  • Neoplasms / pathology
  • Signal Transduction*

Substances

  • Enzyme Inhibitors
  • Alkyl and Aryl Transferases
  • Farnesyltranstransferase
  • GTP-Binding Proteins