Why are some human disease-associated mutations fixed in mice?

Trends Genet. 2003 Dec;19(12):678-81. doi: 10.1016/j.tig.2003.10.002.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Age of Onset
  • Animals
  • Chromosomes*
  • Disease Models, Animal
  • Disease*
  • Humans
  • Mice
  • Mice, Mutant Strains
  • Mutation*
  • Phenotype
  • Phylogeny
  • Selection, Genetic*