Bioinformatics Study with an Implementation of Two Feature Extraction Algorithms for Protein Sequences

Article Preview

Abstract:

Predicting subcellular localizations of proteins is related to multi-label learning. A serial of computational approaches have been developed. This study focuses on the extracting protein features. The feature vector influences the performance of a predicting algorithm significantly. In this paper, two feature extraction algorithms named composition-transition-distribution and class pattern frequency were introduced and implemented in Java, respectively. This program provided a friendly graphical user interface where users can get these two kinds of features easily and quickly. Moreover, the results can be saved into a specified file for later use. Finally, this program can be compressed into a single jar file and runs on a computer which installed the proper JRE. We hope that this program would give researchers some help in the future.

You might also be interested in these eBooks

Info:

Periodical:

Pages:

576-579

Citation:

Online since:

January 2014

Authors:

Export:

Price:

* - Corresponding Author

[1] J.Z. Cao, W.Q. Liu and J.J. He: PLoS One Vol. 8 (2013), p. e67343.

Google Scholar

[2] S. Zhang, X.F. Xia and J.C. Shen: BMC Bioinformatics Vol. 9 (2008), p.127.

Google Scholar

[3] K.C. Chou and H.B. Shen: Anal. Biochem. Vol. 370 (2007), p.1.

Google Scholar

[4] K. Imai and K. Nakai: Proteomics Vol. 10 (2010), p.3970.

Google Scholar

[5] K.C. Chou: J. Theor. Biol. Vol. 273 (2011), p.236.

Google Scholar

[6] P.F. Du, T.T. Li, and X. Wang: Expert Rev. Proteomics Vol. 8 (2011), p.391.

Google Scholar

[7] K.C. Chou: Mol. Biosyst. Vol. 9 (2013), p.1092.

Google Scholar

[8] P. Du and C. Xu: Expert Rev. Proteomics Vol. 10 (2013), p.227.

Google Scholar

[9] I. Dubchak, I. Muchnik, S.R. Holbrook, and S.H. Kim: Proc. Natl. Acad. Sci. USA Vol. 92 (1995), p.8700.

Google Scholar

[10] V. Saravanan and P.T. Lakshmi: submitted to Journal of Acta. Biotheor. (2013).

Google Scholar