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Mitochondrial heat-shock protein hsp60 is essential for assembly of proteins imported into yeast mitochondria

Abstract

A nuclear encoded mitochondrial heat-shock protein hsp60 is required for the assembly into oligomeric complexes of proteins imported into the mitochondrial matrix. hsp60 is a member of the 'chaperonin' class of protein factors, which include the Escherichia coli groEL protein and the Rubisco subunit-binding protein of chloroplasts.

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Cheng, M., Hartl, FU., Martin, J. et al. Mitochondrial heat-shock protein hsp60 is essential for assembly of proteins imported into yeast mitochondria. Nature 337, 620–625 (1989). https://doi.org/10.1038/337620a0

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