Molecular Therapy
Volume 13, Issue 3, March 2006, Pages 494-505
ArticleDesign of Noninflammatory Synthetic siRNA Mediating Potent Gene Silencing in Vivo
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Abbreviations
apoB
apolipoprotein B
TLR
Toll-like receptor
ssRNA
single-stranded RNA
dsRNA
double-stranded RNA
siRNA
short interfering RNA
IFN-α
interferon-α
IL-6
interleukin-6
TNF-α
tumor necrosis factor-α
RNAi
RNA interference
β-gal
β-galactosidase
PBMC
peripheral blood mononuclear cells
Keywords
RNA interference
nucleic acid therapeutics
synthetic siRNA
chemical Modification
inflammatory response
apolipoprotein B
interferons
liposomes
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Copyright © 2005 The American Society of Gene Therapy. Published by Elsevier Inc. All rights reserved.